PPT-Genomics for Cancer Clinicians

6session practical course Genomics into Medicine Session 1 Essential genetics and genomics for clinical practice Dr Polona Le Quesne Stabej University of Auckland 2pm May 27 th 2022 Session 2. NHGRI strategic plan. What does the NIH think genomics should be for the next 10 years?. [Nature, Feb. 2011]. The Essence of Genomics. (according to NHGRI). Comprehensiveness. . Genomics . aims to generate complete data sets. Although relatively easy to define and measure for a genome sequence, attaining comprehensiveness can be more challenging for other targets (for example, functional genomic elements or the ‘proteome’). Bioinformatics and Genomics. Applications:. Personalized cancer medicines. Disease determination . Pathway Analysis. Biomarker Discovery . An Interesting Point. “One . article estimated that the output from genomics may soon dwarf data heavyweights such as . NGS analysis. Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and . . www.hivguidelines.org. Purpose of This Guideline. Provide standards for clinicians in NYS to identify HPV-related anal disease in individuals with HIV . and provide . currently available treatment and follow-up.. February 6, 2013. Howard K. . Koh. , MD, MPH. Assistant Secretary for Health . U.S. Department of Health and Human Services . Progress Review Overview. Summarize the burden of Cancer in the U.S. and the role of Genomics . Familial adenomatous polyposis Key facts • Familial adenomatous polyposis (FAP) is an autosomal dominant condition, resulting in an extremely high risk of colorectal cancer, together with other www.hivguidelines.org. AUGUST 2022. NYSDOH AIDS Institute Clinical Guidelines Program. Purpose of This Guideline. Increase the numbers of NYS residents with HIV who are screened and effectively treated for HPV-related anal and perianal dysplasia.. Views of genomics. [Solve challenges]. [Risks outweigh benefits]. Which of those applications of genomics do you approve of:. applications of genomics. % Approve/somewhat approve. Diagnose and plan treatments for cancer patients. Chromatic modifying genes. Supplementary Figure 1. . Oncoprint. depicting the genomic landscape of MIBC from the TCGA cohort with co-occurring alterations in canonical pathways and cellular functions. Infusion Therapies. Aditya Bardia MD, MPH . Massachusetts General Hospital, . Dana Farber/Harvard Cancer Center,. Harvard Medical School, Boston, MA. .. . No Disclosure. No Relevant Disclosures. . To understand the principle of targeted therapies and importance of routine tumor genotyping in cancer . May . 5, 2015. Key events in investigating the cancer genome. M R Stratton Science 2011;331:1553-1558. Flow . chart of the genome analysis for a cancer . patient . O . Kilpivaara. , and L A . Aaltonen. South West Genomic Laboratory Hub. 23. rd. February 2023. Haem germline findings. NGS testing for MPN. TATs. SNP arrays. WGS. 2. Haem Genomics update. A number of the genes included in haem NGS panels for their somatic actionability are also cancer susceptibility genes (CSGs) in the germline setting e.g. . Supportive & Palliative Care CSG Trials Meeting. 25. th. September 2017. London – The Shard. . Lesley Turner. NCRI Supportive and Palliative Care CSG. Background: . Established in 2014 by Professor Alan Jackson, Southampton BRC and NOCRI . Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and .