PPT-SAR- SULPHONAMIDE Sulphanilamide
Author : garcia | Published Date : 2024-02-09
skeleton is the minimum structural requirement for antibacterial activity The amino and sulphonylgroups on the benzene ring are essential and should be in C4
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SAR- SULPHONAMIDE Sulphanilamide: Transcript
skeleton is the minimum structural requirement for antibacterial activity The amino and sulphonylgroups on the benzene ring are essential and should be in C4 and C1 position The NH2 group at C4 is basic and the NH2 Group at C1Acidic due to Sulfonyl group . Sulphanilamide Crystalluria and the pKa Sulphonamides and their metabolites are excreted almost in the urine. Sulphonamides are not water soluble; they crystallize in the kidney and causes crystalluri Prepared By. Dr. Khalid Ahmad Shadid. Chemistry Department . Islamic university in . madinah. . 1. Introduction. Internal treatment of diseases of microbial origin by the use of chemical compounds which have a specific toxicity to the infecting micro-organisms but are relatively harmless to the infected host is known as . . …………………………………………………………………………………………………………………………………………………………………………………………………………………………………………….
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