PPT-Neuropathology & Genetics of Parkinsonism

Dennis W Dickson MD Department of Neuroscience Mayo Clinic Jacksonville FL Parkinsonism clinical syndrome Macroscopic findings in Parkinsonism Loss of neuromelanin pigmentation of substantia nigra dopaminergic neurons and locus ceruleus noradrenergic neurons. By: Keith King. Objectives. State the history of genetics;. Describe major century events;. Define terms used in genetics . History of Genetics. People have known about inheritance for a long time.. --children resemble their parents. in the Animal Industry. Describe 2 types of selection. Compare Phenotype and Genotype. Define Common Terms used in genetics. Describe the interrelationship between genetics and the environment.. Demonstrate the use of a . Dr Jamie Farmer. Outline. Parkinsonism . vs. PD. Causes of parkinsonism. Akinetic. rigid syndromes. IPD. Signs/symptoms. Examination. Differential diagnosis. Investigations. Management. Complications. Traits. - Characteristic, quality, or feature that distinguishes an organism. Genetics. /Heredity. - . The passing on of traits from parent to offspring. Acquired Trait. - Trait that is learned or obtained through experience or practice.. A. Structure of DNA. 1. discovered by James Watson and Francis Crick in 1953. 2. stores genetic information for the production of proteins. 3. composed of nucleotides. A) a nucleotide is composed of a nitrogenous base, sugar, and phosphate. Objective . Tonight’s Homework. To see how genotype and phenotype apply. pp 127: 2, 5. Finish the “odds” for your kid. Making a Kid Using Genetics. In this activity, you’ll be pairing up with a friend and combining traits to make a kid. One of you will be “mom” and the other will be “dad”. Choose however you want.. Information for patients and families . Christopher Stephen, MD, MRCP (UK). Nutan. Sharma, MD, PhD. X-Linked . Dystonia. -Parkinsonism (XDP). - What is it?. Multiple names. XDP. DYT3 by dystonia classification. Objectives. Identify. traits that vary in populations and that may be studied.. Explain. the importance of the bell curve to population genetics.. Compare . three causes of genetic variation in a population.. Objectives. State the history of genetics;. Describe major century events;. Define terms used in genetics . History of Genetics. People have known about inheritance for a long time.. --children resemble their parents. some or all accepted cardinal signs 147rest148 tremor plastic rigidity delayed initiation movement slowness were recorded on all pa- initial symptoms and date death dura- family history ism or neurolo Richard J Davenport . Edinburgh. The problem. 74 . yr. old male. Shakey. , mainly R hand. ?mother had a shake. Not much else. Is this parkinsonism?. If yes…..is it PD or something else?. If no……what is it?. Stephen Rich. Reporting for the Genetics Committee. March 28, 2019. 8:45am. MESA Genetics Committee. Wednesday, March 27, 2019, 8:30-10pm (Judiciary Suite). Agenda:. Introduction (Rich). MESA Genetics P&P (Post). on child motor development. and implications for learning. Dr Liam JB Hill. . l.j.hill@leeds.ac.uk. @. DrLiamJBHill. . Why discuss the role of genetics in the classroom?. Two thirds of differences in school achievement relate to our “genetic endowment” (. Advisory Board on Toxic Substances and Worker Health. Parkinson Disease Working Group. May 8-9, 2024. SEM . Health Effects: . Parkinsonism (Aliases) . April 12, 2024 . ABTSWH . Parkinson Disorders Recommendation .