PPT-INTRINSIC APOPTOSIS PATHWAY

Marieta Garib Aisha Green Linda Miranda WHAT IS INTRINSIC APOPTOSIS AND WHY DO WE CARE Programmed celldeath involving permeability of mitchondria Involves Caspase9 As opposed to extrinsic. Jalal . Ghasemzadeh. Andrology. lab. Yazd Reproductive Sciences Institute . بسم الله الرحمن الرحیم. Introduction into cell death. In humans. , . the rate of . cell growth . and . cell death . Dr. . Mahvash. Khan. MBBS, MPhil. Hemostasis. The third mechanism by which Hemostasis can be achieved is by formation of a blood clot.. Hemostasis. Hemostasis is prevention of blood loss.. Blood Clot. Necrosis. Apoptosis is a form of programmed cell death. Apoptosis is responsible for the formation of digits in the developing mouse paw. . Apoptotic cells are biochemically recognizable.. Chapter 18. Cell death. Necrotic. Caspase-dependent. Caspase-independent. receptor. -caspase 8. mitochondria. -caspase 9. Classification of cell death. Apoptosis. Apoptosis is programmed cell death, which prevents damage to neighboring cells by controlling how the affected cell dies. Dr. Tania A. . Shakoori. Apoptosis. Apoptosis.  . -. programmed . cell . death. 3 stages. Initiation . (depending on where the . the. signal comes from). Extrinsic. Intrinsic. Execution. Phagocytosis. Examples of apoptosis induction with different kinetics measured by competing technologies such as TUNEL or Annexin . V. Slow induction of apoptosis. Rapid induction of apoptosis. The time point of the measurement is crucial:. Andrology. lab. Yazd Reproductive Sciences Institute . بسم الله الرحمن الرحیم. Introduction into cell death. In humans. , . the rate of . cell growth . and . cell death . is balanced to maintain the weight of the body. . Carcinogenesis. b. y . Michele M. Cox. Department of Biology. University of the Virgin Islands. NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE. A Presentation to Accompany the Case Study:. APOPTOSIS. Lessons leaned. Apoptoti. c process. definition . A . programmed cell death process which. . begins. . when. . a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of . Fibrin. Fibrinogen. Start with the bottom line: fibrin formation. After all, this is what the clotting cascade is designed for. Fibrin. Fibrinogen. 2 ways to get to bottom line:. Intrinsic pathway. Extrinsic pathway. Deptt. . Of Pathology. JNMC, AMU. APOPTOSIS. It is a form of . coordinated and internally programmed . cell death.. The term is derived from a Greek word for “falling off”, coined in 1972 and is different from necrosis. . Novus-lu-2945 novusbio.com novusbio.com Apoptosis is derived from the Greek pre�x apo-, meaning “away, off”, and the word ptosis, meaning “falling, a fall”. IntroductionApoptosis Si Apoptosis, often referred to as programmed cell death, is a tightly regulated and fundamental biological process that plays a crucial role in maintaining tissue homeostasis, development, and defense against various cellular stressors.. LEC.5. 3. Evasion of apoptosis:. Normally, . the mechanism of . apoptosis is mediated by many genes, & achieve by two phases. . Initiation phase. , which is mediated by . TNF- Fas receptor . & inhibited by FLIP protein..