PPT-REPAIR Project Researching the Effects of the Presence and Absence of Ionizing Radiation

SNOLAB Future Projects Workshop July 15 2019 REPAIR collaboration Doug Boreham Research Faculty NOSM Chris Thome Research Faculty NOSM Simon Lees Research Faculty NOSM TC Tai Research Faculty. Jeffrey Bryan, DVM, MS, PhD, DACVIM(Oncology). bryanjn@missouri.edu. Cellular Radiation Effects . Cell membrane - Alteration in permeability. Cellular organelles - Functional Aberrations . Nuclear membrane - Altered permeability & Function . Department of Risk Management and Safety. Machine Produced. Radiation Safety. Training. University of Notre Dame. Risk Management and Safety. Radiation Safety. Overview. Ionizing Radiation. Sources. Effects. Applications. Artificially produced radioisotopes find many uses in agriculture, industry, medicine, forensic science, and scientific research.. The first practical application though of radioactivity was done by George de Hevesy in 1911. . Preconception (the stage is set): . Intergenerational Effects. Genetic. Cultural. Non-genetic Familial Intergenerational Effects. Stress. Diet. Drugs, environmental chemicals. Effects on Development. Jeffrey Bryan, DVM, MS, PhD, DACVIM(Oncology). bryanjn@missouri.edu. Cellular Radiation Effects . Cell membrane - Alteration in permeability. Cellular organelles - Functional Aberrations . Nuclear membrane - Altered permeability & Function . Radiation Biology. Branch of biology concerned with the effects of ionizing radiation on living systems. Includes. Sequence of events occurring after the absorption of energy from ionizing radiation. 1. Type . of. . radiation. charged. . particles. photonen. neutronen. Uncharged. „. particles. “. Charged. . particles. electrons. (. b. -. ). He. 2+ . (. a. ), H. +. (p) D. +. (d). Recoil. Available on the Internet at https//wwwepagov/sites/production/files/201508/documents/522822pdfAvailable on the Internet at https//wwwfaagov/regulationspolicies/advisorycirculars/indexcfm/go/documenti reasons First if ions are formed in livingtissue such as the human body they canelectrical charge they are easy to detect Thismakes it possible to measure the amount ofradiation present even at extrem as in international and national standards The general meaning is unambiguous but a value depends on a number of conditions and the purpose Hence a clear on a numerical value of the energy threshold Radiation refers to the process that is concerned with the passage of energy between places through space. . It is the radiation generated by sun that . regulates the temperature of earth. . . CLASSIFICATION OF RADIATION: ionizing or non-ionizing types. . Radiation.  is a process in which energetic particles or energetic waves travel through vacuum or media. .. Radiobiology.  (also known as radiation biology) is the study of the action of ionizing radiation on living things.. INTRODUCTION . Radiation is energy that moves through space or matter at a very high speed. This energy can be in the form of . particles. , e.g. alpha or beta particles, which are emitted from radioactive materials, or . Jennifer Schroeder, MD. Resources . . Objectives. Cover some basic terminology. What is the target of radiation in living systems. How does the cell cycle play a role. Units and the ridiculousness that it is.