PPT-Metabolism Enzymes: review

Anabolism vs Catabolism What is necessary for a chemical reaction to begin Reactants must come together in the right orientation With enough energy So ho do enzymes catalyze this process Lowers activation energy. Understanding:. Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions. Enzymes lower the activation energy of the chemical reactions that they catalyse. Enzyme inhibitors can be competitive or non-competitive. By Aidan Cross and Tom Grant. How many phases of drug . metabolism are there? (1 mark). 3 Phases. . What . is phase 1 of drug metabolism? (2). Provide a functional group (e.g. OH or NH. 2. ) to:. increase polarity of the drug. Ken Wu. Disclaimer. This tutorial is a simple and conceptual guide to metabolism. If there are any conflicts between my slides and the lecturers, . THE LECTURER IS ALWAYS RIGHT…. …maybe not always but they set your exams so if in doubt, refer back to their teaching. METABOLISM OR BIOTRANSFORMATION . The conversion from one chemical form of a substance to another. . The term metabolism is commonly used probably because products of drug transformation are called . Dr Anissa Atif Mirza. What is Metabolism?. Metabolism is a . network of metabolic /biochemical reactions.. Carried out in living cells.. In a. well organized, integrated and regulated manner.. Related to various biomolecules viz. Disclaimer. This tutorial is a simple and conceptual guide to metabolism. If there are any conflicts between my slides and the lecturers, . THE LECTURER IS ALWAYS RIGHT…. …maybe not always but they set your exams so if in doubt, refer back to their teaching. , RECETOX. www.recetox.cz. BIOMARKERS AND TOXICITY MECHANISMS. 06 . – . Mechanisms. . Metabolism. . & Detoxification. Metabolism and detoxification. Chemicals enter . body . ... mostly . via . Department of Pharmaceutics. . . Drug metabolism or Biotransformation is the major mechanism for elimination of drug from the body.. . It is the process by which the drug is chemically modified . Professor of the Chemistry Department of . DonNMU. . BORZENKO BERTA GEORGIYEVNA. Co-authors: associate . prof. . Elena . Bakurova. , assistant . Kseniia. . Mironova. . . Donetsk National Medical University named after M. Gorky. BC 2.5 Microbiology and Genetics 12 2 6 85 BC 2.6 Quantitative Analysis and Molecular Biology 12 2 6 85 BC 2.7 Viva-Voce -- 1 25 ----- Total marks 90 Turk J Pharm Sc, Publshed by Galenos Publshng House. *Correspondence: eke@pharmacy.ankara.edu.tr, Phone:Receved:Accepted: Bu derlemede flavin-içeren monooksijenazların (F 3rd Stage . College of Pharmacy . Al-. Mustansiriyah. University. Dr. . Basma. Al- . Sudani. Lecture . 5. 27-6-2021. BIOMEDICAL IMPORTANC. Xenobiotics. are a wide variety of foreign chemicals , both naturally occurring compounds in plant foods, and synthetic compounds in medicines, food additives, and environmental pollutants.. west. Prepared By:. Rakiaa. Michael Saeed. Supervised by:. Asst. Prof. Dr. . Gulzar. I. Ibrahim. . Introduction . However, the term . xenobiotics. is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because . enzymes. . . The . substance converted by an enzyme is called a . substrate. , and a substance resulting from the conversion of the substrate is called the . product. . . The . enzyme is not consumed during the reaction catalyzed by it, so one enzyme molecule is involved in the conversion of many substrate molecules .