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CLEVELAND CLINIC JOURNAL OF MEDICINE      VOLUME 73  NUMBER 1       J CLEVELAND CLINIC JOURNAL OF MEDICINE      VOLUME 73  NUMBER 1       J

CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 73 NUMBER 1 J - PDF document

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CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 73 NUMBER 1 J - PPT Presentation

CHRISTOPHER SIBLEYMDDepartment of CardiologyJohns HopkinsUniversityBaltimoreMDNEIL JSTONEMDProfessor of Clinical MedicineFeinbergSchool of MedicineNorthwestern UniversityChicagoIL Familial h ID: 954428

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CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 73 ¥ NUMBER 1 JANUARY 2006 CHRISTOPHER SIBLEY,MDDepartment of Car

diology,Johns HopkinsUniversity,Baltimore,MDNEIL J.STONE,MDProfessor of Clinical Medicine,FeinbergSchool of Medicine,Nort

hwestern University,Chicago,IL Familial hypercholesterolemia:A challenge of diagnosis and therapy REVIEW FH causes charac

teristic tendon xanthomas,especially inthe Achilles tendons,that can be missed unlessspecifically sought.In young white p

atients,arcus corneae or patients with heterozygous FH,statin therapymarkedly reduces LDL-C and is the mainstay of amulti

drug treatment regimen.Patients with homozygousFH are at high risk of premature aortic valvular stenosismultidrug therapy

at an early age.LDL apheresis can becontrol cholesterol levels. M Dr.Stone has indicated that he serves as a consultant

for and has giveneducational talks sponsored by the Abbott,Merck,Merck-Schering,Pfizer,Reliant,and Sonosite corporations.