CHRISTOPHER SIBLEYMDDepartment of CardiologyJohns HopkinsUniversityBaltimoreMDNEIL JSTONEMDProfessor of Clinical MedicineFeinbergSchool of MedicineNorthwestern UniversityChicagoIL Familial h ID: 954428
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CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 73 ¥ NUMBER 1 JANUARY 2006 CHRISTOPHER SIBLEY,MDDepartment of Car
diology,Johns HopkinsUniversity,Baltimore,MDNEIL J.STONE,MDProfessor of Clinical Medicine,FeinbergSchool of Medicine,Nort
hwestern University,Chicago,IL Familial hypercholesterolemia:A challenge of diagnosis and therapy REVIEW FH causes charac
teristic tendon xanthomas,especially inthe Achilles tendons,that can be missed unlessspecifically sought.In young white p
atients,arcus corneae or patients with heterozygous FH,statin therapymarkedly reduces LDL-C and is the mainstay of amulti
drug treatment regimen.Patients with homozygousFH are at high risk of premature aortic valvular stenosismultidrug therapy
at an early age.LDL apheresis can becontrol cholesterol levels. M Dr.Stone has indicated that he serves as a consultant
for and has giveneducational talks sponsored by the Abbott,Merck,Merck-Schering,Pfizer,Reliant,and Sonosite corporations.