PPT-Determinants of rates of serious hypoglycaemic events in type 1 diabetes

Paul McKeigue Institute of Genetics and Molecular Medicine University of Edinburgh Acknowledgements Anita Jeyam Stuart McGurnaghan Helen Colhoun SDRNT1BIO investigators 22 September 2020 Scottish Diabetes Research Network Type 1 Bioresource. Dr. Neil Munro, . Esher. , . United Kingdom. Socio-economic consequences of major hypoglycaemia in T1D and T2D. T1D: 1.1–3.2 major hypoglycaemic events/year. 1. T2D: 0.1–0.7 severe hypoglycaemic events/year (treatment dependent). E with type 2 diabetes mellitus & occurrence of osteoporosis B . S iddhartha Kumar, A. R avisankar, A lladi M ohan, D. P rabath K umar, D.T. K atyarmal, A lok * & K.V. S arma ** Division of Weirui. Chai. 4/12/2011. Content. Diabetes – High Blood . Sugar. Type 1 and Type 2 . Diabetes. Treatments for Type 2 . Diabetes. Conclusion. Diabetes – High Blood Sugar. Diabetes . mellitus:. A . SUs), an oral hypoglycaemic medication (Parkes . et al., . 2014). SUs have the ability to induce hypoglycaemic episodes which can present as dizziness, difficulty concentrating and reduced consciousness. These factors can impact awareness when driving.. IN DIABETICS IN . AFRICANS USING ADEMOLUS CLASSIFICATION OF HYPOGLYCAEMIA. BY DR ADEGBENGA BOLANLE ADEMOLU . MEDICINE DEPARTMENT. LAGOS STATE UNIVERSITY TEACHING HOSPITAL,LAGOS.NIGERIA. . . Efficacy and Safety of Modern Antihyperglycemic Therapies. 1. DPP-4 Inhibitors. 2. DPP-4 Inhibitors. FDA-Approved . Agents. Alogliptin. Linagliptin. Saxagliptin. Sitagliptin. Key . Features. Oral administration. Years from . diagnosis. 0. 5. -10. -5. 10. 15. Pre-diabetes. Onset. Diagnosis. Insulin secretion. Insulin “efficiency”. Ramlo-Halsted BA, Edelman SV. . Prim Care. . 1999;26:771-789 Nathan DM. . N Engl J Med. . Clinical Presentation of Type 2 Diabetes 1 Age ≥45 years Family history of T2D or cardiovascular disease Overweight or obese Sedentary lifestyle Non-Caucasian ancestry Previously identified IGT, IFG, and/or metabolic syndrome Type 2 Diabetes. High blood glucose. Insulin secretion from pancreas. ↑ Glucose absorption by muscle. Low blood glucose. Eat. Analyzed genome sequence of Steve Quake. Rare protein altering SNPs . But usually do not know what the gene does, so difficult to know if the mutation is causing a trait.. Definition. Type 1 Diabetes. : This refers to a genetically based condition in which the cells in the pancreas that normally produce a hormone called “Insulin” stop functioning. This often appears in childhood or early adolescence. The only treatment for Type 1 Diabetes is insulin replacement (by pump or injection). Without adequate supplementary insulin, blood sugar levels dramatically increase and glucose “spills over” into the urine.. Type 1 Diabetes: Before and After Insulin. 1. . The Case for Serendipity. Available at: http://www.mc.vanderbilt.edu/lens/article/?id=221&pg=999. Accessed April 6, 2010.. 2. . Westman. et al. . Perspectives in Biology and Medicine. By:. . Akash Saxena. KLE . College of Pharmacy, . Belagavi. A constituent Unit of KLE Academy of Higher Education and Research. Nehru Nagar, . Belagavi. . –. 590 010, Karnataka, India. Phone:. 0831-2471399;. Download PDF The Diabetes Loophole™ eBook by Reed Wilson - A detailed program aimed at helping you understand and address your body\'s requirements when experiencing diabetes symptoms. Real Food - Real Hope. changing. direction. Jeremy Martin. Ambassador for the PHC. Associate with Think Healthy Me. 2. This . presentation is for information only. . It . is not medical advice. . Please discuss any dietary changes with your doctor....