PPT-PKU & Life Course Development: Birth to Two Years

Development PKU A Life Course Development Perspective PKU amp Life Course Development Birth to Two Years Issues Brain is particularly sensitive to elevated phenylalanine levels. Full Name at Birth First Middle Last 2 Date of Birth Month Day Year Sex Age Last Birthday 3 Place of Birth Kentucky City or Town Kentucky County Name of Hospital 4 Mothers Maiden Name First iddle Last 5 Fathers Name First Middle Last If this child h Keyp = Mutated PKU Gene birth rate death rateCC WageDeath/Birth ratewHw0 death rate birth rate EUE0EH 0 200 400 600 800Number of Outbreaks per Decade 1300 1400 1500 1600 1700 1800Year 0 5 10 15 20 25p.c. tax revenue / wage 0 By: Adrienne Gebele. What is PKU?. 1. Inherited disorder. Occurrence varied due to ethnicity and geography. About 1 and 10,000 to 15,000 infants are born with in the U.S.. People born with PKU have an inactive liver enzyme which causes a dangerous build up of phenylalanine in the blood. on Topological. . Science and Topological . Matters. Kyoto . University & Peking University . Feb. 13-18, 2017, Kyoto (Japan). Organiziners. Guo-qing. . Zheng. Okayama University. Ippei. . Danshita. By Kevin Zhu, Walter Chen, and. Sachin Patro. Definition. Phenylketonuria (PKU) is a genetic disorder that is described by an lack of ability of the body to use the necessary amino acid called phenylalanine. Amino acids are the building blocks for body’s proteins. 'Essential' amino acids can only be attained from the food that we eat. Our body does not normally produce them. The 'classic PKU', the enzyme that breaks down phenylalanine hydroxylase, is absolutely or almost completely lacking. This enzyme normally turns phenylalanine to another amino acid called tyrosine. Without this ‘Classic PKU', phenylalanine and it’s other breakdown chemicals from other enzyme method, build up in the blood and body tissues. . What is PKU?. PKU is an inherited disorder that is an error of metabolism that increases the levels of a substance in the blood called phenylalanine hydroxylase.. Phenylalanine is an important amino acid and the body needs it for health; you get it from food. It is a building block for proteins in the body.. Home birth. A woman booked in for a home birth must ensure the following are provided:. A clean, well ventilated room with adequate heating and lighting. A comfortable bed for the mother and plastic sheets to protect the mattress. Denise M. Ney, PhD, RD . Professor of Nutritional Sciences . Waisman Center. University of Wisconsin-Madison . Disclosure. D Ney is a co-inventor on US Patent Application US-2010-0317597, GMP Medical Foods for Nutritional Management of PKU, which is held by the Wisconsin Alumni Research Foundation and licensed to . Executive Director. . 529 adults, families, and professionals in the PKU community. 8 countries. 32 states. The NPKUA works to improve the lives of individuals and families with PKU and pursue a cure.. FYI. We hope you find these modified presentations of help in the current situation of being able to provide Parent Education classes. You can find lots of information on the hospital website . www.hdft.nhs.uk. f the NPKUA. Justin Young, DDS, MD. Sarah Foster, MPS. Founding Co-Chairs. Speaker Conflict of Interest Statement. Justin Young . . Nothing to disclose. Sarah Foster. . Employee of Applied Nutrition, manufacturers of medical food for PKU and other inborn errors of metabolism. Cary O. Harding, MD. Department of Molecular & Medical Genetics. Disclosures. BioMarin Corporation. Funds for participation in clinical trials. Sapropterin dihydrochloride. rAvPAL-PEG. National PKU Alliance. Supervised by: Dr. . Nuhad. . Alduri. . Prepared by : . zahraa. . basim. . mohammed. Phenylketonuria. Phenylketonuria, an inborn error of metabolism inherited as an autosomal recessive trait (the PAH gene is located on chromosome 12q24), is caused by a deficiency or absence of the enzyme needed to metabolize the essential amino acid phenylalanine. Classic PKU is at one end of a spectrum of conditions known as .