PPT-Immunoglobulins (1 of 2)

Ali Al Khader MD Faculty of Medicine AlBalqa Applied University Email alialkhaderbauedujo Immunoglobulins Igs antibodies Each B cell synthesizes Igs of single specificity for a specific epitope. Dr. . Nasim. PGT Biochemistry. Antibodies. Proteins that recognize and bind to a particular antigen with very high . specificity. .. Made in response to exposure to the antigen.. Each antibody has at least two identical sites that bind antigen: . Recall Structure . Numerous V region genes are preceded by Leader or signal sequences (60-90 . bp. ) . exons. interspersed with . introns. .. Heavy chain contains . V (Variable), D . (Diversity), . J (Joining) and C (Constant) . Cells of the Immune System. Physical & Chemical Barriers. Innate and Adaptive Immunity. Innate Defenses. Nonspecific physical and chemical barriers that contribute to resistance against infection. WHO Essential . Medicines. List . Animal (equine) derived blood products . Snake anti-venom immunoglobulins . Anti-rabies imunoglobulins. Anti- tetanus immunolglobulins. Anti-diphtheria immunoglobulins. David Lowe. Royal Free Hospital / University College London. Or…. Suspecting primary immunodeficiency. AND. Suspecting secondary . hypogammaglobulinemia. Primary immunodeficiency (…in adults). Antibodies / B cells. - Definition, Structure & Function, . Classes of . Immunoglobulins. ).. - Antibodies . are . glycoprotein . molecules that . recognise a . particular . epitope. on . an antigen. , bind specifically . - . ontogenesis. , . surface. . markers. , . function. . . . Ontogenesis. . of. . antibody. . production. .    . 16. . Immunoglobulins. (. structure. , . classes. ). . Genetic. . background . Dr. . Vinod. K.V.. Also known as antibodies. They are . glycoproteins. produced by the body against antigenic stimulus. Synthesised by B lymphocytes. Basic structure. Igs. are . glycoproteins. Made up of two pairs of polypeptide chains. Lec.4. . Dr. Mustafa Jawad. Definition of Immunoglobulins (Igs). Immunoglobulins, also known as . antibodies. , are glycoprotein molecules produced by . plasma cells . (B-cell). . They . act as a critical part of the immune response by specifically . Martin Liška. 1. The structure of immunoglobulins. 2. Isotypes. (in principle) classes of antibodies distinguished on the basis of H chain structure differences. 5 types: . m. (IgM), . d. (IgD), . also known as antibodies, are glycoprotein molecules produced by plasma cells (white blood cells). They act as a critical part of the immune response by specifically recognizing and binding to particular antigens, such as bacteria or viruses, and aiding in their destruction.. Immunoglobulin Genes. immunoglobulins. The two hallmarks of . immunoglobulins. as antigen-binding proteins are the . specificity of each for a particular epitope target and their diversity as a group. In addition to antigen binding, however, .