Consultant PediatrcianPedicare Ratu Roadrchsssidanarediffmailcom Alleviation of Pain Associated ID: 955360
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735V 17, 2009practitioners. There is a mention of demerits of theconjugate Vi vaccine marketed in India in the IAPTypically any new vaccine (or for that matter anynew drug) has to undergo phase 1 (early safety anddosing study), phase 2 (safety, dosing andimmunogenicity study) and phase 3 (field efficacydo efficacy trials and can be licensed provided itwill assume and extrapolate similar efficacy for theis called bridging studies)(3). The new brand has toHowever if the serological correlates ofchoice but to conduct field efficacy trials to provevaccines for which huge and expensive field efficacyunconjugated Vi vaccine, oral Ty21a vaccine or thereason why for each of the
se vaccines field efficacytrials have been conducted and reported(5). This isconducting field efficacy trails with their owncandidate conjugate Vi vaccine(2). drnitinshah@hotmail.com.1.Singhal T, Amdekar Y, Agarwal R. IAP Guidebook2.Clemens J. Translational research to generate3.Jódar L, Butler J, Carlone G, Dagan R, Goldblatt D,4.Cherry JD. Comparative efficacy of acellularpertussis vaccines: an analysis of recent trials.5.Engels EA, Matthew EF, Joseph L, Michael LB.others prescribe Thrombophob ointment application,besides paracetamol. What is the stand of IAP on this Consultant Pediatrcian,Pedicare, Ratu Road,rch_sssidana@rediffmail.com. Alleviation of Pain Associate