PPT-Non-Destructive and Rapid Skeletal Visualization in DART studies

Michael Johnson 1 Thomas Villani 1 Nick Crider 1 Colleen Wojenski 2 1 Visikol Inc North Brunswick NJ 08902 2 Product Safety Labs Dayton NJ 08810 Abstract Developmental and reproductive toxicology DART studies are required for new chemical entities going to market to ensure that there are not adverse developmental consequences associated with the chemical These studies involve dosing a pregnant female animal eg mouse rat rabbit with the compound and evaluating the effect of the chemical on the offspring This evaluation involves the parallel processes of histopathology and gross morphological evaluation wherein the most timeconsuming component of DART studies is the performance of gross skeletal evaluation Since the introduction of Thalidomide into the marketplace close attention has been paid to the impact of chemicals on skeletal development and DART studies require the visualization of gross skeletal morphology for abnormalities The current methodology for conducting skeletal evaluation involves digesting soft tissue using a strong base potassium hydroxide and staining the bone with alizarin and cartilage in some cases with . of biological events in cell cultures - The HoloMonitor™ 2 What is a HoloMonitor ™ ? A HoloMonitor™ is a totally non-inva - sive live-cell microscope/cell analyzer for adherent cel Experience Maps (Me Museum, Journey) (please put maps on front desk) •Blink! Which one conveys the most information at-a-glance? Does the personality of the Me Museum honoree come across? •D Innovation Studies. Luc . Soete. Maastricht University. The . N. etherlands. “The Intellectual legacy of Christopher Freeman”, 5. th. -6. th. November 2015, Institute of Economics, . Scuola. . BY. Grant Mefford. Poisonous Dart Frog. Can be many different colors ; yellow, orange, red, green and blue.. Does not have ears.. Has four legs.. Eats insects. Can live 3-15 years in the wild. Only grows to be ½ - 2 inches. Steering Committee Meeting . December 4, 2012. Agenda for RTS Steering Committee. Introductions and Purpose of Meeting . . Steering Committee Mission and Schedule . Overview. . of Studies and Reports on . Presented By. Cheryl D. Orr, SPHR, IPMA-SCP. Vice President of Human Capital. June 20, 2017. MAX Program. – Partnership with DART, LA METRO, MARTA, RTD. Leadership DART . – Partnership with Southern Methodist University. WEBEX. Welcome. Kathy Hayman. Director, Business Processes. KMI Pipelines. Agenda. Project Status & Sandbox Opening. General Dart Navigation. IT & Pool Contracts. IT & Pool Nominations. Q&A. William Chow. April 12, 2012. Introduction. Darts is an accuracy game. Speed-accuracy trade-off. Many versions of darts. American darts. Archery darts. Cricket. Dart golf. Round the clock. Fives. Halve it. The Office of Board Support. Laneshia Hawkins. Board Support Specialist. June 19, 2017. Agenda. History of the DART Board . Function of the Board . Board Member Appointments. Board Meetings. Functions of the Office of Board Support. Safety & Security Campaign. Spring 2012. to Present. Dallas Area Rapid Transit 2013 Stats. Geographic . Service . Area: 13 . cities, 700 square . miles. 612 buses/12,500 stops (. 38.7 million passenger . x0000x0000Page of Faye Wilkins 150DART Era to an EndDART Board Chair Sue Bauman Faye Wilkins DART Board Member Mark Enoch and DART President/ExecMrs Wilkins gives farewellspeechat DART Board Meetingx0 INTRODUCTION. PROGRAMMING LANGUAGE DART. Open-source. Structured. Flexible. Developed by Google. Primarly used for Web applications, but with new version, Dart is used even in Mobile applications and in Desktop applications. 1. Overview. Object Oriented Language. Developed By Google. Primarily used for building websites, servers, and mobile apps. Provides librariries, an editor, a virtual machine (VM) and a compiler to javaScript. DART PROGRAMMING. Contents. Setup. Fundamentals. Data Types. String. Type Conversion. Constant. Null. Operators. Loops. Collection [List, Set, Map]. Function . Class. Exception Handling. Setup Dart SDK.