PPT-Neisseria Meningitidis (Meningococcus)

General features Gramnegative diplococci Catalase and oxidase positive Nonmotile aerobic Pathogens Neisseria gonorrhoeae Neisseria meningitidis Commensals N lactamica N flavescens N mucosa N sicca N subflava. Source National Center for Health Statistics bridged race vintage 20 12 postcensal file ABCs Case Definition eningococcal disease isolation of Neisseria meningitidis from normally sterile site in a resident of a surveillance area in 2012 ABCs Method Presented by: . Seyed. . Davar. . Siadat. (. Ph.D. ). Pasteur Institute of Iran. 1. WHAT ARE OMVs. ?. BASIC RESEARC!. 1- Small spherical structures 20–250 nm in diameter. . 2- Produced by growing cells, not products of cell . Aman. Sidhu . Origin of Bacterial Meningitis . Meningitis belt of Africa . Extends from the eastern side (ETHIOPIA) to the western end (Senegal). Highest outbreak seen in regions that fall under the belt . You are paged by the Microbiology Lab and told that blood . cultures drawn from your patient, Mrs. I. M. Septic, are growing . gram-positive . cocci. . Mrs. Septic is a 42-year-old woman who was. admitted with a fever and malaise. Which of the following is NOT . cultures drawn from your patient, Mrs. I. M. Septic, are growing . gram-positive . cocci. . Mrs. Septic is a 42-year-old woman who was. admitted with a fever and malaise. Which of the following is NOT . honour. of . dr.Albert. . Neisser. who in 1879 discovered the organism causing . gonorrhoea. . . Definition:. Paired, gram negative . cocci. with adjacent sides flattened aerobic and poor . Abdulwahid. . University of . Mustanisiriya. College of Medicine . Third stage . The Neisseria. Gram-negative . cocci. , usually occur in pairs to form (. diplococci. ). The two medically important species are . Received: February 5, 2012/ Revised: February 14, 2012 Accepted: February 17, 2012Corresponding author: Kyungwon Lee, M.D., Ph.D. Department of Laboratory Medicine and Research Institute of Bacterial Singhal S, Purnapatre KP, Kalia V, Dube S, Nair D, Deb M, et al. Ciprofloxacin-Resistant Neisseria meningitidis, Delhi, India. Emerg Infect Dis. 2007;13(10):1614-1616. https://doi.org/10.3201/eid1310.060820. Neisseria. spp.. Gram’s negative Diplococci . Kidney shape with flat opposing edge. Neisseria. spp.. PATHOGENIC:. N. gonorrhoea. (gonococci, G.C) . . Gonorrhoeae. .. N. meningitidis. Nolfi-Donegan D, Konar M, Vianzon V, MacNeil J, Cooper J, Lurie P, et al. Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab. Emerg Infect Dis. 2018;24(8):1561-1564. https://doi.org/10.3201/eid2408.180228. Lab # 6. NEISSERIA SPECIES. Contains many species; 2 are human pathogens. Neisseria . gonorrhoea. (gonococcus). Neisseria . meningitidis. (. meningococcus. ). Other species are normal flora that inhabit the upper respiratory tract of humans.. Virulence Factors. ™. Pili or fimbriae - . Adhesion to host cells & prevent phagocytosis. ™. Outer membrane proteins – . - . Porin. (protein I) . - >50% of OMP. - PorB.1A strains - local and disseminated . jabar. . Aldhaher. Neisseria. The genus Neisseria contains two important pathogens: . 1. Neisseria meningitidis . 2. Neisseria gonorrhoeae. . N. meningitidis causes meningitis and meningococcemia. .