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Symmetry Definition:   Both limbs are behaving identically Symmetry Definition:   Both limbs are behaving identically

Symmetry Definition: Both limbs are behaving identically - PowerPoint Presentation

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Symmetry Definition: Both limbs are behaving identically - PPT Presentation

Measures of Symmetry Symmetry Index Symmetry Ratio Statistical Methods James Richards modified by W Rose Symmetry Index SI when it 0 the gait is symmetrical Differences are reported against their average value If a large asymmetry is present the average value does not correctly reflec ID: 783350

trend symmetry unbraced range symmetry trend range unbraced braced amputee eigenvector offset amplitude normalcy shift joint analysis ratio phase

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Slide1

Symmetry

Definition: Both limbs are behaving identicallyMeasures of Symmetry Symmetry IndexSymmetry RatioStatistical Methods

James Richards, modified by W. Rose

Slide2

Symmetry Index

SI when it = 0, the gait is symmetricalDifferences are reported against their average value. If a large asymmetry is present, the average value does not correctly reflect the performance of either limbRobinson RO, Herzog W, Nigg BM. Use of force platform variables to quantify the effects of chiropractic manipulation on gait symmetry. J Manipulative Physiol Ther 1987;10(4):172–6.

Slide3

Symmetry Ratio

Limitations: relatively small asymmetry and a failure to provide info regarding location of asymmetryLow sensitivitySeliktar R, Mizrahi J. Some gait characteristics of below-knee amputees and their reflection on the ground reaction forces. Eng Med 1986;15(1):27–34.

Slide4

Statistical Measures of Symmetry

Correlation CoefficientsPrincipal Component AnalysisAnalysis of Variance

Use single points or limited set of points

Do not analyze the entire waveform

Sadeghi H, et al. Symmetry and limb dominance in able-bodied gait: a

review. Gait Posture 2000;12(1):34–45.

Sadeghi H, Allard P, Duhaime M. Functional gait asymmetry in ablebodied subjects. Hum Movement Sci 1997;16:243–58.

Slide5

The measure of trend symmetry utilizes eigenvectors to compare time-normalized right leg and left leg gait cycles in the following manner. Each waveform is translated by subtracting its mean value from every value in the waveform.

for every ith pair of n rows of waveform data

Eigenvector Analysis

Slide6

Eigenvector Analysis

Translated data points from the right and left waveforms are entered into a matrix (M), where each pair of points is a row. The rectangular matrix M is premultiplied by its transpose to form a 2x2 matrix

S:

S = M

T

M

The eigenvalues and eigenvectors of S are computed.

Slide7

Eigenvector Analysis

To simplify the calculation process, we applied singular value decomposition (SVD) to the translated matrix M to determine the eigenvalues and eigenvectors of S=MTM,

since SVD performs the operations of multiplying M by its transpose and extracting the eigenvectors

. Note that the singular values of M are the non-negative square roots of the eigenvalues of S=M

T

M (as stated by

Labview

help).

Slide8

Eigenvector Analysis

Each row of M is then rotated by (minus) the angle formed between the eigenvector and the X-axis, so that the points lie around the X-axis (Eq. (2)):

w

here

a

nd e

x

and

e

y

are the x and y components of the (largest) eigenvector of S, and a 4-quadrant inverse tangent function is used.

 

Slide9

Eigenvector Analysis

The variability of the rotated points in the X and Y directions is then calculated. The Y-axis variability is the variability perpendicular to the eigenvector, and the X-axis variability is the variability along the eigenvector.

Compute the ratio

of the variability about the eigenvector

to the

variability along the

eigenvector. This number will always be between 0 and 1. The ratio is subtracted from 1, giving the Trend Symmetry, which will be between 1 and 0.

 

Slide10

Eigenvector Analysis

Trend Symmetry = 1.0 indicates perfect symmetryTrend Symmetry = 0.0 indicates lack of symmetry.

The Trend Symmetry will be 1 if the ratio of

variabilities

is 0. This will occur if and only if the rotated points all lie on the X axis (which means the variability along Y is zero).

The Trend Symmetry will be 0 if the ratio of

variabilities

is 1. This will occur if the rotated points vary as much in the Y direction as they do in the X direction.

 

Slide11

Additional

measures of symmetry: Range amplitude ratio quantifies the difference in range of motion of each limb, and is calculated by dividing the range of motion of the right limb from that of the left limb.

Range offset

, a measure of the differences in operating range of each limb, is calculated by subtracting the average of the right side waveform from the average of the left side waveform.

 

Slide12

Eigenvector Analysis

Trend Symmetry: 0.948

Range Amplitude Ratio: 0.79, Range Offset:0

 

Slide13

Eigenvector Analysis

Range Amplitude Ratio: 2.0

Trend Symmetry: 1.0, Range Offset: 19.45

 

Slide14

Eigenvector Analysis

Range Offset: 10.0

Trend Symmetry: 1.0, Range Amplitude Ratio: 1.0

 

Slide15

Eigenvector Analysis

Trend Symmetry: 0.979 Range Amplitude Ratio: 0.77 Range Offset: 2.9

°

Raw flexion/extension waveforms from an ankle

Slide16

Eigenvector Analysis

Slide17

Final Adjustment #1

Determining Phase Shift and the Maximum Trend Symmetry: Shift one waveform in 1-percent increments (e.g. sample 100 becomes sample 1, sample 1 becomes sample 2…) and recalculate the trend symmetry for each shift. The phase offset is the shift which produces the largest value for trend symmetry. The associated maximum trend symmetry value

is also noted.

Slide18

Final Adjustment #2

Trend Symmetry (TS), as defined so far, is unaffected if one of the waves is multiplied by -1. Therefore Trend Symmetry, as computed, does not distinguish between symmetry and anti-symmetry. We can modify Trend Symmetry to distinguish between symmetric and anti-symmetric waveforms:

 

Slide19

Final Adjustment #2

TS

mod

=

1.0 indicates perfect

symmetry.

TS

mod

= -1.0 indicates perfect

antisymmetry

.

TS

mod

= 0.0 indicates complete lack of symmetry.

 

Slide20

Symmetry Example

Slide21

Hip Joint

Trend Symmetry

Phase Shift (% Cycle

Max Trend Symmetry

Range Amplitude

Range Offset

95% CI

0.98 – 1.00

-3.1 – 2.9

0.99 – 1.00

0.88 - 1.16

-5.99 – 5.66

Unbraced

1.00

1

1.00

0.95

4.21

Braced

1.00

0

1.00

1.02

4.73

Amputee

1.00

-1

1.00

0.88

-0.72

Symmetry Example…Hip Joint

Braced

Amputee

Unbraced

Slide22

Knee Joint

Trend Symmetry

Phase Shift (% Cycle

Max Trend Symmetry

Range Amplitude

Range Offset

95% CI

0.97 – 1.00

-2.6 – 2.5

0.99 – 1.00

0.87 - 1.16

-8.95 - 10.51

Unbraced

1.00

0

1.00

1.03

5.28

Braced

1.00

-1

1.00

0.99

6.40

Amputee

0.98

-1

0.99

0.91

4.15

Symmetry Example…Knee Joint

Braced

Amputee

Unbraced

Slide23

Ankle Joint

Trend Symmetry

Phase Shift (% Cycle

Max Trend Symmetry

Range Amplitude

Range Offset

95% CI

0.94 – 1.00

-2.62 – 2.34

0.96 – 1.00

0.75 - 1.32

-6.4 – 7.0

Unbraced

0.98

-1

0.98

1.03

-2.96

Braced

0.73

-4

0.79

0.53

5.84

Amputee

0.58

4

0.61

1.27

0.48

Symmetry Example…Ankle Joint

Unbraced

Braced

Amputee

Slide24

Normalcy Example

Slide25

Hip Joint

Trend Normalcy

Phase Shift (% Cycle

Max Trend Normalcy

Range Amplitude

Range Offset

95% CI

0.98 – 1.00

-3.1 – 2.9

0.99 – 1.00

0.88 - 1.16

-5.99 – 5.66

Right hip

Unbraced

1.00

2

1.00

0.85

-14.91

Braced

0.99

3

1.00

0.90

-14.20

Amputee

0.97

-4

1.00

0.92

-8.08

Left hip

Unbraced

Braced

Amputee

Unbraced

Braced

Amputee

Slide26

Hip Joint

Trend Normalcy

Phase Shift (% Cycle

Max Trend Normalcy

Range Amplitude

Range Offset

95% CI

0.98 – 1.00

-3.1 – 2.9

0.99 – 1.00

0.88 - 1.16

-5.99 – 5.66

Right hip

Unbraced

Braced

Amputee

Left hip

Unbraced

1.00

2

1.00

0.91

-19.28

Braced

0.99

4

1.00

0.91

-19.09

Amputee

0.99

-2

1.00

1.06

-7.52

Unbraced

Braced

Amputee

Slide27

Knee Joint

Trend Normalcy

Phase Shift (% Cycle

Max Trend Normalcy

Range Amplitude

Range Offset

95% CI

0.97 – 1.00

-2.6 – 2.5

0.99 – 1.00

0.87 - 1.16

-8.95 – 10.51

Right knee

Unbraced

0.99

1

0.99

1.12

-11.89

Braced

0.98

3

0.99

1.07

-13.22

Amputee

0.96

-2

0.99

0.97

-7.45

Left knee

Unbraced

Braced

Amputee

Unbraced

Braced

Amputee

Slide28

Knee Joint

Trend Normalcy

Phase Shift (% Cycle

Max Trend Normalcy

Range Amplitude

Range Offset

95% CI

0.97 – 1.00

-2.6 – 2.5

0.99 – 1.00

0.87 - 1.16

-8.95 – 10.51

Right knee

Unbraced

Braced

Amputee

Left knee

Unbraced

0.99

1

0.99

1.11

-16.35

Braced

0.97

4

0.99

1.10

-18.80

Amputee

0.98

-2

1.00

1.08

-10.78

Unbraced

Braced

Amputee

Slide29

Ankle Joint

Trend Normalcy

Phase Shift (% Cycle

Max Trend Normalcy

Range Amplitude

Range Offset

95% CI

0.94 – 1.00

-2.62 – 2.34

0.96 – 1.00

0.75 - 1.32

-6.4 – 7.0

Right ankle

Unbraced

0.90

-2

0.94

1.48

1.33

Braced

0.65

-4

0.72

0.77

9.04

Amputee

0.80

-5

0.98

1.40

4.30

Left ankle

Unbraced

Braced

Amputee

Unbraced

Braced

Amputee

Slide30

Ankle Joint

Trend Normalcy

Phase Shift (% Cycle

Max Trend Normalcy

Range Amplitude

Range Offset

95% CI

0.94 – 1.00

-2.62 – 2.34

0.96 – 1.00

0.75 - 1.32

-6.4 – 7.0

Right ankle

Unbraced

Braced

Amputee

Left ankle

Unbraced

0.93

-1

0.95

1.49

4.62

Braced

0.94

2

0.95

1.51

3.53

Amputee

0.11

-11

0.76

1.14

4.15

Unbraced

Braced

Amputee

Slide31

Simpler way to compute Trend Symmetry

No need for SVD or Eigen-routines.Can be done in an Excel spreadsheet.Compute 2x2 covariance matrix:

Note s

12

=s

21

.

Eigenvalues of

S are the values of

which satisfy:

 

Slide32

Simpler way to compute Trend Symmetry

Eigenvalues of S are the values of which satisfy :

 

Slide33

Ratio of smaller to larger eigenvalue:

where

Then