PPT-Antifungal Therapy in Immunocompromised Patient

 Immunocompromised An Immunocompromised host is a patient who does not have the ability to respond normally to an infection due to an impaired or weekend immune system This inability to fight infection can be caused by a number of conditions including. ). 22 novembre 2013. . Dr S. . Alfandari. Médecin Référent en antibiothérapie et Hygiéniste, CH Tourcoing. Infectiologue Consultant, Service des Maladies du sang, CHRU Lille. www.infectio-lille.com. an antigen . to stimulate the immune response through active . immunity. Stimulates . the proliferation of T and B cells, resulting in the formation of effector and . memory. . cells – stimulates acquired immunity without disease pathology. Chapter 4. Introduction. Molecules recognized as “non-self” are antigens. Several mechanisms to protect itself . First level of protection include physical and biochemical-skin, acid in stomach. Second level of protection phagocytic cells, enzymes, and proteins. Josef . Jampílek. Department of Pharmaceutical Chemistry. Faculty of Pharmacy. Comenius University. . in Bratislava, Slovakia. Present situation. Preparation of nanoparticles/nanoformulations. of existing drugs. Kouros. . Aghazade. . Shahid. . Beheshti. Medical University. . Candidiasis. Spectrum of Infection. Images courtesy of Kenneth V. Rolston, MD, and John R. Wingard, MD.. Walsh et al. . Infect Dis Clin North Am. university. college of pharmacy. Pharmaceutical chemistry. Antifungal drugs. Fungi . are traditionally important in plant pathology.. They . have gained much importance for causing serious . human diseases. ) . (. Lecture-3 . : Dated . 21.05.2021. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. (Lecture-2 : Dated . 19.05.2021. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Cristiane Del Cioppo. Meily. Gomez. Mindy Huang. Mary Lewis. Rebekah . Philogene. Systemic and Topical Antifungal Medications. First antifungal drugs:. Until the late 1940’s fungal infections were . How??. Dr . Punit. D. . Ghetia. . MD,IDCCM (MUMBAI). Consultant . Intensivist. . Banker’s Heart Institute.. INTRODUCTION. Fungal isolates are now the fourth most common cause of nosocomial blood-stream infection. . Olympia Resol, RN, MPH, CRNI, CARN. Course Objectives. At the end of the course, the student should be able to:. Identify the most common reasons for IV therapy;. Determine who can give IV therapy orders;. II. Synthetic . Antifungal . Drugs. III. Other . Antifungal Drugs. 1. Antifungal antibiotics:. Amphotericin. . (. amphotericin. B. ). Is . a mixture of antifungal substances derived from cultures of . . Pareek. 1. Challenge. Eukaryotes. Difficult to find selective toxicity in eukaryotes than prokaryotes. Fungal infections r more frequent as opportunistic infections in immunocompromised. Cell membrane essential component- sterol. (Lecture-1. . : Dated 12.05.2021). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna.