PPT-Screening of endophytic actinomycetes for antifungal potential and cytotoxicity

Ezza Ashraf 1 Rabia Tanvir 1 Aftab Ahmad Anjum 1 and Hassan Mushtaq 2 1 Institute of Microbiology IOM University of Veterinary and Animal Sciences UVAS Lahore 54000 Punjab Pakistan. and their antifungal activity against phytopathogens in vitro arayan Chandra Paul Seung Hyun Ji Jian Xin Deng 2 and Seung Hun Yu Department of Agricultural Biology College of Agriculture and Life Sciences Chungnam National University Daejeon 305 7 Murray Brown. Manager, Data Interpretation and Business Process. Screening and Compound Profiling. Drug Discovery Process. Basic . Research. Lead . Discovery. Preclinical . Development. Clinical . Development. Index. What is Cytotoxicity ( introduction). Applications :-. Testing Pharmaceuticals. Anticancer Drug Screening. Predictive Drug Testing For Tumors. What is Cytotoxicity ?. Cytotoxicity is the degree to which an agent has specific destructive action on certain cells. Davies-. Bolorunduro. O.F. . 1,2. ,. Adeleye I.A.. 1 . and Wang P.G.. 2 . 1. Department of Microbiology, University of Lagos, . Akoka. , Lagos, Nigeria. 2. Department of Chemistry, Georgia State University, Atlanta, Georgia, U.S.A.. 1. BIOPROSPECTING FOR ANTIMICROBIAL AND ANTICANCER COMPOUNDS FROM ACTINOMYCETES FROM LAGOS LAGOON SEDIMENTS. . Professor . I.A. . Adeleye. Dr. M.O. . Akinleye. 2. BACKGROUND . OF STUDY. . About 23,000 bioactive secondary metabolites produced by microorganism have been reported and over 10,000 of these compounds are produced by . t Available online a Pelagia Research LibraryEuropean Journal of Experimental Biology, 2015, 5(9):20-26 ISSN: 2248                        List of Acronyms/Abbreviations x          & Antioxidant assays. Total phenol content (mg of GAE/g of extract). Total flavonoid content (mg of QE/g of extract). DPPH radical scavenging activity. ABTS radical scavenging activity. . . Ferric reducing power assay. Loynachan. Citation: Thomas . Loynachan. . 2008. Soil actinomycetes.. Publication Date : June 2008. Introduction. . Actinomycetes is a nontaxonomic term for a group of common soil microorganisms sometimes called "thread or ray bacteria." They are known for decomposing more resistant organic materials such as chitin, a complex sugar found in the outer skeleton of insects and elsewhere. Actinomycetes are simple prokaryotic organisms that are gram positive, have a high G+C base composition, and are mycelium (thread) forming. Nucleic materials (DNA) consist of a helical structure with a sugar backbone attached through the bases adenine – thymine (A+T) and guanine – cytosine (G+C). Compared with the DNA of other organisms, actinomycetes have a high percentage of guanine – cytosine bases. In growth habit, many actinomycetes resemble fungi but are smaller, and terms common to both are used to describe morphological features. The most common genus of actinomycetes in soil is . Zetty. . Norhana. . Balia. . Yusof. , PhD. Department of Biochemistry,. Faculty of Biotechnology and Biomolecular Sciences,. Universiti. Putra Malaysia,. 43400 UPM,. Serdang. , Selangor,. MALAYSIA. Intended Use:ecommended for detection of saccharolytic marine bacteria.Composition** Ingredients Gms / Litre powder 1.000 Starch 10.000 Sea water 37.000 Agar 15.000 Final pH ( at 25°C) 7.2±0.2**For Tulsi. and Neem plant extracts with their related endophytic actinomycetes against ESBL producers. Hafsa Shahzadi. 1. , . Rabia Tanvir. 1. , Ali Ahmad Sheikh. 1. and Wasim Shehzad. 2. 1. Institute of Microbiology (IOM), University of Veterinary and Animal Sciences (UVAS), Lahore 54000, Punjab, Pakistan. Anne O Hara (Senior Medical Scientist). Microbiology Department . Beaumont Hospital. Dr Alida. . Fe Talento (C.H.I.), Dr Binu Dinesh, Dr Karina O Connell, . Dr Sinead O’Donnell, . Prof. Fidelma Fitzpatrick, Prof. Karen Burns, Ms Margaret Fitzpatrick.. Rhodotorula. -P5 induces a priming effect in . Ulmus. minor. promoting the protection against . Ophiostoma. novo-. ulmi. Juan Sobrino-Plata. , Sara M. . Ormeño. , Iván Fernández, . Corné. M.J. .