PPT-Perspectives of Antifungal Drug Discovery

Josef Jampílek Department of Pharmaceutical Chemistry Faculty of Pharmacy Comenius University in Bratislava Slovakia Present situation Preparation of nanoparticlesnanoformulations of existing drugs. By Andreas Dr Lorenz M.Mayr Drug Discovery World Summer 2006 Miniaturisation ofassay developmentand screening In recent years we have seen a strong increase in the number of chemicalcompounds and mole an Industrial Process. How are drugs . discovered and developed?. Dr Steve Carney, s.carney@elsevier.com. Managing Editor, . Drug Discovery Today. What’s my background?. First degree in Biochemistry. Fungi. Also known as mycoses. Very large and diverse group of microorganisms. Of major two . types: . yeasts and molds.. Mycotic. Infections:. Cutaneous. Subcutaneous. Superficial. Systemic: . Can be life-threatening. – . get ready for the show. Weidong Zhang. Pfizer. 1. Outline. Overview of omics technology. Application of omics in drug discovery. Case studies from pre-clinical to phase II/III. 2. 3. Omics provide paramount view of biological cascade. Properties: . Optimizing Pharmacokinetics and Safety During Drug . Discovery. ACS Short Course. Li Di and Edward H. Kerns. Introduction to Drug-Like Properties. Few research compounds will become drugs because they lack sufficient pharmacokinetics (PK) and safety. Distinguished University Professor Lecture. Presented on January 29, 2015 by Paul Erhardt, PhD. UT DUP and Director of the Center for Drug Design and Development (CD3). paul.erhardt@utoledo.edu. 1. Outline. Please Sign Up:. . Name. . Email (. Onyen. is fine, or …). . Are You . ENRolled. ?. Dept. & Advisor (Lab?). . Tentative Title (“????” Is OK). . When:. Next Week, Early, Oct., Nov., Late. 30 -1-2017. Dr. . Naza. M. Ali. Antifungal Drugs . . Unlike bacteria, fungi are eukaryotic.. Fungal infections are generally resistant to . . antibiotics used in the treatment of bacterial . Also known as mycoses. Very large and diverse group of microorganisms. Of major two . types: . yeasts and molds.. Mycotic. Infections:. Cutaneous. Subcutaneous. Superficial. Systemic: . Can be life-threatening. (Lecture-2 : Dated . 19.05.2021. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. . fungi-cide or fungi-static. . They are used to treat in the treatment and prevention of mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others. . Gerald J. Wyckoff. Training modes. Are we training . genomicists. to deal with the right problems?. Are the training modalities we’re using proper?. What questions should we be looking at?. Problems in Drug Discovery. II. Synthetic . Antifungal . Drugs. III. Other . Antifungal Drugs. 1. Antifungal antibiotics:. Amphotericin. . (. amphotericin. B. ). Is . a mixture of antifungal substances derived from cultures of . 1. Dr. Abd El Raheim Donia. Generally,. . a drug . can be . defined . as a . substance that . induces . a response . within the human . body.. Dr. Abd El Raheim Donia. 2. FDA Definition . of a . Drug.