PPT-Antifungal Agents ( Part-II)

Lecture2 Dated 19052021 Dr Nirbhay Kumar Asstt Professor amp Head Deptt of Veterinary Pharmacology amp Toxicology Bihar Veterinary College Bihar Animal Sciences University Patna. Fungi. Also known as mycoses. Very large and diverse group of microorganisms. Of major two . types: . yeasts and molds.. Mycotic. Infections:. Cutaneous. Subcutaneous. Superficial. Systemic: . Can be life-threatening. 30 -1-2017. Dr. . Naza. M. Ali. Antifungal Drugs . . Unlike bacteria, fungi are eukaryotic.. Fungal infections are generally resistant to . . antibiotics used in the treatment of bacterial . Also known as mycoses. Very large and diverse group of microorganisms. Of major two . types: . yeasts and molds.. Mycotic. Infections:. Cutaneous. Subcutaneous. Superficial. Systemic: . Can be life-threatening. Josef . Jampílek. Department of Pharmaceutical Chemistry. Faculty of Pharmacy. Comenius University. . in Bratislava, Slovakia. Present situation. Preparation of nanoparticles/nanoformulations. of existing drugs. Styrylquinoline. Derivatives. Hana Michnova. 1,2,. *, . Sarka. Pospisilova. 1,2. , . Ewelina. Spaczynska. 3. , . Wioleta. Cieslik. 3. ,. Alois. Cizek. 2. , Robert Musiol. 3. and Josef Jampilek. university. college of pharmacy. Pharmaceutical chemistry. Antifungal drugs. Fungi . are traditionally important in plant pathology.. They . have gained much importance for causing serious . human diseases. ) . (. Lecture-3 . : Dated . 21.05.2021. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Cristiane Del Cioppo. Meily. Gomez. Mindy Huang. Mary Lewis. Rebekah . Philogene. Systemic and Topical Antifungal Medications. First antifungal drugs:. Until the late 1940’s fungal infections were . . fungi-cide or fungi-static. . They are used to treat in the treatment and prevention of mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others. . II. Synthetic . Antifungal . Drugs. III. Other . Antifungal Drugs. 1. Antifungal antibiotics:. Amphotericin. . (. amphotericin. B. ). Is . a mixture of antifungal substances derived from cultures of . . Pareek. 1. Challenge. Eukaryotes. Difficult to find selective toxicity in eukaryotes than prokaryotes. Fungal infections r more frequent as opportunistic infections in immunocompromised. Cell membrane essential component- sterol. . (. Drugs used in the treatment of fungal infections). Natural. . origin: Amphotericin B, . Nystatin, Griseofulvin, . . Natamycin (. Pimaricin. ), . Echinocandins. Acknowledgments. Addis Ababa University. Jimma. University. Hawassa. University. Haramaya. University. University of Gondar. American Society for Clinical Pathology. Center of Disease control and Prevention in Ethiopia.. (Lecture-1. . : Dated 12.05.2021). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna.