PPT-Serotonin & Anti-serotonin drugs

At the end of this session students should be able to Describe serotonin 5HT receptors including serotonin amp antiserotonin drugs Explain important clinical applications of serotonin related drugs. (PHR5001). Lecture 6:. ANTIDEPRESSANT . DRUGS. Dr. M G . Azam. Asstt. . Professor. Dept. of Pharmacy, NSU. 1. Depression. Thought to result from a deficiency of . norepinephrine. or serotonin. Antidepressants. antidepressants. Sarah & Clara. Depression: . Most common mental health issue. ICD-10: Mood [affective] disorders (F30-F39). . Key symptoms:. 1) Persistent low mood/sadness and/or. 2) marked loss of interest or pleasure. Major Psychiatric Disorders . Psychoses. eg schizophrenia. Affective disorders. . eg depression and mania. Psychoses . False perceptions (Hallucinations). False beliefs (Delusions). Affective Disorders . . Dr. Sameer Al- Rekabi. . Autacoids = local . hormones. DEFINITION. These are heterogeneous group of chemical substances with wide spectrum of biological effects , synthesized by different tissues and exerting local effect with no or very minute serum level.. Synaptic . Transmission & . Neurotransmitters . September 24, 2012. Ashkan Afshin. Review Sessions. September 17, 2012. 7:30-8:30pm. Pathogenesis. September 24, 2012. 7:30-8:30pm. Neuropathophysiology. Projects. Molecular Mechanism of Drug Action and Side Effects. Form teams (A,B,…) (check them online, under ‘News’). Install ICM-browser (link online). Pick a disease-target centered project . David Chen. 11307120002. What is serotonin?. Neurotransmitter(. 神经递质. ). Also called 5-hydrotrptamine(. 5-HT. )5-. 羟色胺. Synthesized from . tryptphan. How does this system work?. Fig. from . What is drug misuse and drug abuse?. What is addiction?. Understand basic ideas about how drugs may influence transmission of action potentials from pre-synaptic neuron to post-synaptic neuron.. You do NOT need to memorize the individual effects of each of the drugs. You SHOULD be able to understand and explain such statements as “Drug X blocks the serotonin re-uptake protein on the pre-synaptic neuron”.. Opioid analgesics. Antidepressant drugs. Antipsychotic drugs. Antidepressant drugs. Pathophysiology of Major Depression. Classification of antidepressant drugs. Therapeutics . uses and adverse effects . Paige Lipski. Overview of coagulation. In health components of coagulation all present in circulation and only become activated when injury occurs. Injury results in:. -vasoconstriction to reduce blood loss and assist platelet adhesion. By. Bohlooli. S., Ph.D.. School of Medicine, Ardabil University of Medical Sciences. Introduction. The diagnosis of depression still rests primarily on the clinical . interview. Antidepressant . drugs were the most commonly prescribed medications in the . Diuretics. Sympathoplegic agents. Direct vasodilators. Agents that block action of angiotensin. Most anti-HT drugs ↓ BP by ↓ CO &/or ↓ PVR. Mechanisms for Controlling Blood Pressure (BP):. Mild HT can be controlled with a single drug;. Rationale-. . Telangana. Rationale-. Covid-19, has been a major public health concern worldwide. India announced lockdown on 23rd March 2020, which led to halt of all the outpatient services, sample transportation and Anti TB drug delivery.. INTRODUCTION. Leprosy is a chronic infectious disease caused by . Mycobacterium . leprae. . . OR. Leprosy . is a chronic, communicable disease spread by prolonged, intimate contact with an infected person.