PPT-Serotonin & Anti-serotonin drugs

At the end of this session students should be able to Describe serotonin 5HT receptors including serotonin amp antiserotonin drugs Explain important clinical applications of serotonin related drugs. (PHR5001). Lecture 6:. ANTIDEPRESSANT . DRUGS. Dr. M G . Azam. Asstt. . Professor. Dept. of Pharmacy, NSU. 1. Depression. Thought to result from a deficiency of . norepinephrine. or serotonin. Antidepressants. antidepressants. Sarah & Clara. Depression: . Most common mental health issue. ICD-10: Mood [affective] disorders (F30-F39). . Key symptoms:. 1) Persistent low mood/sadness and/or. 2) marked loss of interest or pleasure. . Dr. Sameer Al- Rekabi. . Autacoids = local . hormones. DEFINITION. These are heterogeneous group of chemical substances with wide spectrum of biological effects , synthesized by different tissues and exerting local effect with no or very minute serum level.. Synaptic . Transmission & . Neurotransmitters . September 24, 2012. Ashkan Afshin. Review Sessions. September 17, 2012. 7:30-8:30pm. Pathogenesis. September 24, 2012. 7:30-8:30pm. Neuropathophysiology. Projects. Molecular Mechanism of Drug Action and Side Effects. Form teams (A,B,…) (check them online, under ‘News’). Install ICM-browser (link online). Pick a disease-target centered project . David Chen. 11307120002. What is serotonin?. Neurotransmitter(. 神经递质. ). Also called 5-hydrotrptamine(. 5-HT. )5-. 羟色胺. Synthesized from . tryptphan. How does this system work?. Fig. from . Nuerotransmitters. How to balance your brain naturally. Neurotransmitters are chemical messengers that help relay information throughout the body. . They . transmit information through nerve cells called neurons. . in . the. . Brain. Median Forebrain Bundle (MFB) . is the “reward center”. C. ontains . nerve cells . that contain . dopamine. , a pleasure-causing neurotransmitter. . . When stimulated by drugs of abuse (cocaine, meth, nicotine, . Assist. Professor. Dr. . Haitham. M. . Alwali. Ph.D. Pharmacology. Al-. Nahrain. College of Pharmacy. 3/15/2018. 1. Serotonin& . the Ergot Alkaloids. S. erotonin. (5-hydroxytryptamine. ; 5-HT) is . APM Resident Education Curriculum. Thomas W. Heinrich, M.D.. Associate Professor of Psychiatry & Family Medicine. Chief, Psychiatric Consult Service at . Froedtert. Hospital. Department of Psychiatry & Behavioral Medicine. 4. th. Stage . Dr. Dalia . Abd. Al- Kader. PhD Pharmacology. Sympathomimetics. are stimulants that mimic the sympathetic nervous system.. produce a relative increase of adrenergic neurotransmitters at their sites of action. Thomas Jefferson University. Class of 2016. Objectives. Identify symptoms of serotonin syndrome. Identify medications at risk to cause syndrome development. Identify possible differential diagnoses. Discuss appropriate syndrome treatment. indolamine. , plays a role in mood, . sleep,pain. . sensitivity, appetite, sexuality, and impulse . control. tryptophan is converted to serotonin . (5-hydroxytryptamine. ) by the enzyme tryptophan hydroxylase as well as by an amino acid . &. new. (this file include 2 lectures) . Objectives:. . Realize neurotransmitter defects in different types of depression.. Elaborate on how antidepressants generally act.. Classify the existing antidepressant into elder (TCAs & MAO Is) and newer groups (SSRIs, SNRIs, NRIs, NAASs, NDRIs, SARIs). .