PPT-Chapter 14 – Inheritance and Disorders

Complex Patterns of Inheritance Incomplete dominance review CoDominance review Multiple alleles pattern of inheritance is determined by two or more alleles Blood types next slide three forms I. This presentation . builds on session 1 exploring patterns of inheritance. Patterns of inheritance. The objectives of this presentation are to:. Understand how genes are inherited. Understand the differences between the inheritance patterns associated with Autosomal dominant, Autosomal recessive, X-linked recessive and chromosomal abnormalities. INTRODUCTION TO GENETICS. APPLIED GENETICS. Chapter 14A: INTRODUCTION TO GENETICS. Mendel. Rules and Terminology for Examination of Genetic Inheritance. Expanding the Rules and Terminology to follow two (or more) genes in a cross. 1. Inheritance. Inheritance. allows a software developer to derive a new class from an existing one. The existing class is called the . parent class,. or . superclass. , or . base class. The derived class is called the . 13.2 Only. : Chromosomal Basis of Inherited Disorders . General Biology I. BSC 2010. Download for free at . http://cnx.org/contents/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.61. Figure 13.5. This karyotype is of a female human. Notice that homologous chromosomes are the same size, and have the same centromere positions and banding patterns. A human male would have an XY chromosome pair instead of the XX pair shown. (credit: Andreas . 11.1 Basic Patterns of Human Inheritance. 11.2 Complex Patterns of Inheritance. EQ: What is the difference between sex linked genes and genes found on autosomal chromosomes? . Chromosomes and Phenotype. Genetic disorders can be due to any of the following factors:. A. Monogenetic Disorders: Caused by a mutation in a single gene. Autosomal. recessive alleles:. a. You may be a carrier and not know it, since the dominant allele masks the recessive.. Polydactyly. Down Syndrome. Hemophelia. Progeria. Hypertrichosis. Sickle Cell Anaemia. INTRODUCTION. What is genetic diseases/disorders?. The human body is composed up of cells , each one specializing a particular function like sensing light, smelling . 1. Chromosomal Theory of Inheritance. Theodor . Boveri. Walter Sutton. In 1902, Walter Sutton and Theodor . Boveri. developed the . Chromosome Theory of Inheritance. . . This theory basically states that Mendelian genes have a specific locus on the chromosome and that chromosomes undergo segregation and independent assortment during meiosis. . 12.1 Chromosomal Inheritance . 1. Genes are located on chromosomes; this is called the . chromosome theory of inheritance. .. 12.1 Chromosomal Inheritance. Chromosomes can be categorized as two types:. Every trait is represented by 2 genes, one from the . father. and the other from the . mother. . When the 2 genes for any given trait are similar, the person is . homozygous . for this trait . If the 2 genes are different, the person is . The production of gametes (sex cells). Males = spermatogenesis in the testes. Females = oogenesis in the ovaries. Mitosis vs Meiosis. (Remember). . Diploid. Contain the full number (set) of chromosomes. Inheriting Genetic Conditions Reprinted from https://ghr.nlm.nih.gov/ Lister Hill National Center for Biomedical Communications U.S. National Library of Medicine National Institutes of Health Departm 4. M. . Faiyaz-Ul-Haque. , PhD, . FRCPath. Atypical Patterns of Inheritance. Lecture Objectives. By the end of this lecture, students should be able to appreciate the possibility of atypical patterns of inheritance with special emphasis on:. TERMINOLOGY OF GENETIC AND CONGENITAL DISORDERS. Congenital. Allele. Gene locus. Gene mutation. Genotype. Phenotype. Homozygous. Heterozygous. Polymorphism. Gene penetrance. Gene expression. CAUSES OF BIRTH DEFECTS.