PPT-An Ontology for Host-Microbiome Interactions

Jihad Obeid MD SCTR Retreat May 2017 MultiInstitutional Collaboration University of Michigan Yongqun Oliver He DVM PhD Haihe Wang MD PhD visiting scholar from Harbin Medical University China. 1. 32. Copyright © McGraw-Hill Global Education Holdings, LLC. Permission required for reproduction or display.. Microbial Interactions…. Symbiosis = an association of two or more different species of . Intermediate outcomes. Broad outcomes. Human-microbe interactions. Living systems are interconnected and interacting. . While microbes can harm us, we require interactions with them to survive. . Microbes interact with humans in various ways, beneficial, neutral, and detrimental.. Yongqun. . “Oliver” He. Unit for Laboratory Animal Medicine. Department of Microbiology and Immunology. Center for Computational Medicine and Bioinformatics. University of Michigan Medical School. Eat your Yogurt. . Biotics. : . Pre-, Pro, . Syn. - . and Antibiotics. Biotics . refers to . Bacteria. Staphylococcus aureus. Nomenclature & Definitions. Microorganism:. Largely unicellular organisms that need optical magnification to be seen. Alexander V. Alekseyenko. Biomedical Informatics Center. Departments of Public Health Sciences and Oral Health Sciences. Program for Human Microbiome Research. Medical University of South Carolina. Acknowledgments. Human genome. Maternal diet. Mode of birth. Antibiotics . Timing of birth. NICU admission. Infant diet. Environment. Background:. Bacteria . (≥60%), viruses, eukaryotes, archaea. Gut. largest reservoir (≥30 genera & 500 species). Paer. Amir Zarrinpar, MD, PhD. Assistant Professor. Division of Gastroenterology. Institute for Diabetes and Metabolic Health. Center for Microbiome Innovation. VA San Diego GI Obesity and NAFLD/NASH Clinic. Dr. Christine K. . Chege. Microbiome. Symposium. Kenya . Paediatric. Association Annual Conference. 10. th. . April 2019. Definition of . microbiome. The collective . genomes. of microbes that live . GSQQYRMGEXMSRERHKIRIXMGTVSGIWWIWSJVYQIR QMGVSFIWLSWXKIRSQMGEPP]PMROIHXSQIXLERI IQMWWMSRW 1E Ron . Collman. , MD - University of Pennsylvania. Dirk Dittmer, PhD - University of North Carolina. The Microbiome. The totality of microbial residents living in concert with the human body, along with their genes, functions, products. H. uman health. Agriculture. Nutrient cycling. Environmental remediation . Where ever humans go we bring microbes with us!. Space 101 : Microbes. “Microbes . maketh. man”. Jamie Foster . –. University of Florida. Xabier. López-Alforja. 1. *, David López-Escardó. 1. , Manuel Martínez García. 2. , Sheree Yau. 3. , Ramon Massana. 1. , Felipe H. Coutinho. 1. & Dolors Vaqué. 1.  . DB. nº query scaffolds . Elizabeth Bess. University of Utah. Non-covalent interactions with Pi systems. Overview: . Non-covalent interactions are the underpinnings of chemical selectivity, molecular recognition, and supramolecular molecules’ tertiary structure (e.g., enzymes and DNA). These through-space, rather than through-bond, interactions arise from attractions between oppositely and fully or partially charged species. One such class of non-covalent interactions are the intermolecular interactions of pi systems with other pi systems or charged species. . M. Abdullah. 1. st. . semester . 2018-2019. Computer Science Dept., College of . CS & IT, . Basrah. University. Lecture # . 2. OUTLINE. What’s Ontology?. Ontology in Semantic Web.. Web Ontology Language ..