PPT-Microbiome Data Integration and Biomarker Development

Alexander V Alekseyenko Biomedical Informatics Center Departments of Public Health Sciences and Oral Health Sciences Program for Human Microbiome Research Medical University of South Carolina Acknowledgments. Practices & Experiences. Shawn Li, M.D., Ph.D.. October 1, 2012. Introduction. Frontage Capabilities and Approaches. Case Studies. Challenges and Solutions:. Measurement of . Analyte. in Presence of Endogenous Protein. Biomarker Potential and . Limitations of . Circulating miRNA. Performed by the . Data Management . a. nd Resource Repository (DMRR). ERCC . D. ata Analysis. 1. Williams Z., et al. . (. 2013. ) Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations. Lunch and Learn. May 7, 2015. Deb . Kirchhof. -Glazier. The U.S. is #1 in the world for health care expenditure but…. We are 53 . out of all 228 nations/territories on the globe for . life . expectancy. Neil P. Shull, Ph.D., J.D.. Sterne, Kessler, Goldstein & Fox P.L.L.C.. F.I.R.E. Series LXIX. March 8, 2012. Overview of issues. . What can be patented?. Is it useful?. How much data is needed?. Potential prior art issues. Christopher . Jennison. , University of Bath. Robert A. Beckman, Daiichi Sankyo Pharmaceutical Development and University of California at San Francisco. Agenda. TOPIC 1: Where do subgroups come from? Empirical data or basic science? How does this vary as a function of developmental stage? . Microbiome Therapeutics Market report published by Value Market Research is an in-depth analysis of the market covering its size, share, value, growth and current trends for the period of 2018-2025 based on the historical data. This research report delivers recent developments of major manufacturers with their respective market share. In addition, it also delivers detailed analysis of regional and country market. View More @ https://www.valuemarketresearch.com/report/microbiome-therapeutics-market Microorganisms found across all three domains of life. Bacteria. Archaea. Eukarya. The Biology of Microorganisms- . Eukarya. Although we typically think of members of the domain . Eukarya. as being large, multi-celled organisms, there are in fact many eukaryotic microbes. Human genome. Maternal diet. Mode of birth. Antibiotics . Timing of birth. NICU admission. Infant diet. Environment. Background:. Bacteria . (≥60%), viruses, eukaryotes, archaea. Gut. largest reservoir (≥30 genera & 500 species). Authors: . Kieu Vu, John . Arend. , Nichole . Cadez. , Deb Darnell, Valerie . Somma. , . Randi Rycroft, . Loria. Pollack, . Paran. . Pordell. . Women’s Wellness Connection. BCCP (Triple negative breast cancer). Healthy:. . . A population of 10. 14. bacteria of at least 1000 species and belonging to four major phyla, the majority (90%) . . of which are anaerobes (e.g. Bacteriodetes). Unhealthy: . Paer. Amir Zarrinpar, MD, PhD. Assistant Professor. Division of Gastroenterology. Institute for Diabetes and Metabolic Health. Center for Microbiome Innovation. VA San Diego GI Obesity and NAFLD/NASH Clinic. Ron . Collman. , MD - University of Pennsylvania. Dirk Dittmer, PhD - University of North Carolina. The Microbiome. The totality of microbial residents living in concert with the human body, along with their genes, functions, products. H. uman health. Agriculture. Nutrient cycling. Environmental remediation . Where ever humans go we bring microbes with us!. Space 101 : Microbes. “Microbes . maketh. man”. Jamie Foster . –. University of Florida. Limitations of . Circulating miRNA. Performed by the . Data Management . a. nd Resource Repository (DMRR). ERCC . D. ata Analysis. 1. Williams Z., et al. . (. 2013. ) Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations.