PPT-Session - Safety of DTG in Pregnancy: Late Breaking Findings, Interpretations, Implications

July 24 2018 Overview on Safety of HIV Treatment in Pregnancy Lynne M Mofenson MD Senior HIV Technical Advisor Elizabeth Glaser Pediatric AIDS Foundation HIV Pregnancy and ART HIV is associated . 2 04 06 Nm Time UTC 123 4 m 123 4 Figure 2 Breaking scale 05 01 02 brk c 1 05 01 02 03 brk c 2 05 01 02 03 brk c 3 05 01 02 03 brk c 4 Figure 3 brPage 6br EZ EZ v 05 10 87226 10 87225 10 87224 10 87223 cc c m 87222 s Figure 4 Total breaking rate ZZ b Producing a good piece of coursework. Learning Objectives. To be able to understand the skills required to produce a good interpretations coursework.. Success Criteria. To have looked at/ produced an improved way of completing the Interpretations coursework.. The International . Conference on Automation Science and Engineering . (CASE), . is the flagship automation conference of the IEEE . Robotics and Automation Society (RAS) and is the . primary forum for cross-industry and multidisciplinary research in . L/O – To explore how different versions of the past arise. Starter. – Write a short paragraph describing what your first day at KCCIS was like. Think about feelings, expectations, enjoyment, incidents, friends etc…. Matthew 15:3-9. Man’s Interpretations. Interpret - to . explain or tell the meaning of : present in understandable terms” . (. Merriam-Webster. ). 4 . For God commanded, saying, “Honor your father and your mother’; and, ‘He who curses father or mother, let him be put to death.’ 5 But you say, “Whoever says to his father or mother, ‘Whatever profit you might have received from me is a gift to God”— Matthew . and 22. nd. International AIDS Conference . Selected Pediatric, PMTCT, . and Maternal/Adult. Abstracts. Lynne Mofenson MD 08/06/2018. webinar version. Main Subject - . Everything Dolutegravir. Studies in HIV-Infected Adults/Adolescents. and 22. nd. International AIDS Conference . Selected Pediatric, PMTCT, . and Maternal/Adult. Abstracts. Lynne Mofenson MD 08/06/2018. webinar version. Main Subject - . Everything Dolutegravir. Studies in HIV-Infected Adults/Adolescents. July 23 2018 . What We Know About Safety Signals with DTG Use in Pregnancy. Lynne M. Mofenson MD. Senior HIV Technical Advisor. Elizabeth Glaser Pediatric AIDS Foundation. Dolutegravir. There have been only limited data on DTG in pregnancy and breastfeeding. . Joseph J. Eron, Jr, MD. Professor of Medicine. University of North Carolina. Chapel Hill, North Carolina. Financial Relationships With Commercial Entities. Dr Eron has served as an ad hoc consultant to Janssen, ViiV Healthcare, Merck, and Gilead Sciences, Inc. His institution receives contracts for clinical research on which Dr Eron is the local principal investigator from Janssen Therapeutics, ViiV Healthcare, and Gilead Sciences, Inc. Paul E. Sax, MD. Professor of Medicine. Harvard Medical School and Brigham and Women’s Hospital. Boston, Massachusetts. Financial Relationships With Ineligible Companies (Formerly Described as Commercial Interests by the ACCME) Within the Last 2 Years:. –. NAIVE ADULTS WITH HIV-1 INFECTION: 96-WEEK RESULTS FROM THE GEMINI STUDIES. 1. Fundación Huesped, Buenos Aires, Argentina; . 2. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico; . GEMINI 1 and GEMINI 2: Week 48 Data. DTG + 3TC . versus . DTG + TDF-FTC as Initial ART. GEMINI 1 and 2: Background. Source: Cahn P, et al. Lancet. 2019;393:143-55.. Study Design: GEMINI 1 and 2. Background. ADVANCE. . Design. Primary endpoint. Proportion of patients with HIV RNA < 50 c/mL at W48, ITT-E snapshot analysis ; non-inferiority of TFA/FTC if lower margin CI for . the difference = - 10%, 80% power. Andrew Hill, Francois Venter, Eric . Delaporte. , . Simiso. Sokhela, Charles . Kouanfack. , . Michelle Moorhouse. , Kaitlyn McCann, Bryony Simmons. , . Alexandra . Calmy. Disclosures. Speaker fees and honoraria from Gilead Sciences, AbbVie, Cipla, Johnson and Johnson, Sanofi, Pfizer, ViiV Healthcare, Mylan and Southern African HIV Clinicians Society.