PPT-3.3:DNA Structure

331 Outline DNA nucleotide structure in terms of sugar deoxyribose base and phosphate 332 State the names of the four bases in DNA 333 Outline how DNA nucleotides are linked together by covalent bonds. DNA is composed of polynucleotide chains. The helical structure of . DNA. Formation of Nucleotides. Structure of polynucleotide polymer. Each base has its preferred . tautomeric. form. Purine. and . Nucleic Acids. What do we know already?. i. . The nucleic acids DNA and RNA are polymers of nucleotides. Nucleotides consist of 3 parts. A 5-carbon sugar – ribose or deoxyribose. A phosphate group (acidic & negatively-charged). Lecture 1. An introduction to DNA Topology. DNA. DNA inside the . Nuclues. . The human cell contains 23 pairs of chromosomes. If we scale the cell nucleus to the size of Basketball then the DNA scales to 200km in length.. THINK ABOUT IT. The DNA molecule must somehow specify how to assemble proteins, which are needed to regulate the various functions of each cell.. What kind of structure could serve this purpose without varying from cell to cell?. shapes and patterns. 조연우. Contents. DNA. DNA origami. The application of DNA origami. DNA origami structure. “Normal DNA”. 이중나선 형태로 존재. Double Stranded, Double Helix. Adenine, Thymine, Guanine, Cytosine . DNA damage DNA gets damaged a lot ! DNA damage DNA gets damaged a lot! >200,000 events/human cell/day DNA damage Occurs 2 ways 1) spontaneously 2) mutagens : damage DNA Transposons Discovered by Barbara McClintock The formation of a highly organized DNA-protein complex, termed as chromatin, which is a nucleoprotein complex completes the packing.. Chromatin can be defined as highly condensed chromosomes at metaphase stage, and very diffuse structures in course of . The helical structure of . DNA. Formation of Nucleotides. Structure of polynucleotide polymer. Each base has its preferred . tautomeric. form. Purine. and . Pyrimidine. Base . tautomers. ; are frequent sources of errors during DNA synthesis.  . Author: Michael Fenech. Affiliation: Genome Health Foundation, North Brighton, SA, 5048, Australia. Email: . mf.ghf@outlook.com. . Introduction. Life as we know it depends entirely on the capacity of cells to utilize energy and molecules in the environment for cellular function and reproduction. . (Chapters 6 and 3). . Presented by Dr. Laurie M. Erickson. Chair of the Department of Health Sciences. Blitstein Institute of Hebrew Theological College. Chicago, IL, USA.. 1. 6.1 Genome Size. Genome:. Chapter 16.1. Life. ’. s Operating Instructions. In 1953, James Watson and Francis Crick introduced an elegant double-helical model for the structure of deoxyribonucleic acid, or DNA. Hereditary information is encoded in DNA . 16 Atomic structure of DNA,by Madeleine Price Ball (Wikimedia Commons) Topic Objectives TaskBloom’sBIOL 102 CoreCoreto explain DNA polarity notationtemperature on DNA structure MOLECULAR GENETICS . What is DNA?. DNA is a . Nucleic Acid in the nucleus. Polymer of . Nucleotides. Each nucleotide consists of. Deoxy. ribose (5-carbon sugar) . Phosphate group. a nitrogen-containing base. Four bases. DNA Structure Simulation. Before we begin, let’s investigate the way DNA molecules are set up!. http://learn.genetics.utah.edu/content/molecules/builddna/. The Structure of DNA. What is DNA?. A bit about DNA….