Facilitating Self-Healing; - PowerPoint Presentation

Slide1

Facilitating Self-Healing;

Concomitant with Medications

Millennia Ruth Lytle ND, MPH, CNS aka “Dr. Millie”

www.milliesays.om

millielytle@gmail.comSlide2

Introduction

To facilitate the body’s innate ability to heal

itself is a principle of NM

70% of Americans taking at least one prescription medication and up to 50% taking

two.

85% are taking at least one over-the-counter medications

NM includes

responding to the secondary effects of iatrogenic

interventions

Setting Intention

for nutritional intervention

Beyond essential nutrition and orthomolecular medicine –

What

is the role of nutrigenomics as a tool for improving vital force to overcome drug-induced diseaseSlide3

Learning Objectives

Consider the normal capacity of healing

for the typical American patient

Review common

pharmaceutical obstacles to cure

Consider the healing deficit

Address Naturopathic treatment intentionInvestigate new mechanisms Slide4

Iatrogenesis

In the United States medical error results in 44 000-98 000 unnecessary deaths each year 1

 000 000 excess

injuries

BMJ

. 2000 Mar 18; 320(7237): 774–777.

Where do nutrient depletions fit in

Men who

died

of a sudden ischemic heart attack

had very

low levels of magnesium and potassium in the heart muscle as compared to others who had a heart attack, but who did not

die death

as a result of cardiac arrest could be dependent on levels of electrolytes available.

Am

J

Clin

Nutr

.

 1979 May;32(5):967-70Slide5

Common Prescription medications

Common meds that cause nutrient depletions

Antibiotics

Statins

HRT

Acid blockers

Antidepressants

Anxiety Medications

Blood Pressure Medications

Breathing Medications

Cohen, S. Drug Muggers. 2011Slide6

Mechanisms of Drug-Nutrient depletion

Interfere with absorptionAltered metabolism

Increased ExcretionSlide7

Common Nutrient Depletions

Medications are not studied for their depletions

To facilitate healing we must integrate

the reversal of nutrient

depletions into SOAP

CoQ10

Magnesium

Glutathione

Fat soluble Vitamins

Omega 3s

Iron

Vitamin C

Vitamin B complex

and

Folic

Acid

Probiotics

Cohen, S. Drug Muggers. 2011Slide8

What is the healing deficit? Slide9

Rats treated with 8 mg/kg Adriamycin intravenously 4 days prior to chamber implantation develop impaired wound healing in a wound chamber model. Slide10

How medicine is changing the picture of N

Modifying metabolic biomarkers standards

FPG

rising 0.14mmol to 0.18

mmol

/L per decade from1980 and 2008

Lancet. 2011 Jul 2;378(9785):31-40.Diabetes definition <6.0 mmol/L . New standards <6.5 - <7.0 mmol/L. Int

J

Prev

Med. 2010 Summer; 1(3): 187–194

.

Modifying

measurement

standards

Global mean total cholesterol was 4.6-4.7 in 2008, and was highest in North America 5.23-5.24

mmol

/L. Lancet. 2011 Feb 12;377(9765):578-86.

New Risk Algorithms for targeting risk of CVD at 5-7.5%. Indian Heart J. 2014 Jan; 66(1): 1–4

.Slide11

Prioritizing Medications over Nutrition

FDA says only drugs treat, regardless of research http://

www.fda.gov/downloads/Food/DietarySupplements/UCM240978.pdf

Young and healthier patients on meds

New guidelines propose statins for everyone 40–79 years old, with LD >70 mg/& estimated 10-year risk of hard CV disease is >5.0% risk

Circulation.

 2014 Jun 24;129(25 Suppl 2):S1-45

.

Vilifying Vitamins and Supplements

Over prescribing Coumadin; Avoidance

of vitamin K, Probiotics or natural clotting

mechanisms

Warnings about antioxidants, Fish Oils–

drug studies using synthetic versions or exceedingly high

levels

RDAs remain low and based on 2000 calorie diet.

Reduced availability i.e. Potassium

– banned by FDA for supplementation at RDA levelsSlide12

FDA’s Position

Unlike

drugs, supplements are not intended to treat, diagnose, prevent, or cure diseases. That means supplements should not make claims, such as “reduces arthritic pain” or “treats heart disease.” Claims like these can only legitimately be made for drugs, not dietary supplements

.

– FDA-

http://www.fda.gov/downloads/Food/DietarySupplements/UCM240978.pdfSlide13

Intention

RDAsOrthomolecular medicine

A

ntioxidants

Whole

foods nutrition as nutrigenomic entities

Unclaimed antioxidants – NrF2 Nutrigenomic cascade for cell detox and methylationIntroduce effect of pharmaceuticals on nutrigenomic capabilities of the cellresent research on medications that impede NrF2 expressionSlide14

Critical role of essential nutrients

Medical misunderstanding

Role of iron deficiency anemia in cardiovascular disease

Nutrients important for bones

Levels of Vitamin D3 required for immune health

Vitamin K2’s role in bone health

trace

minerals for bone

repair

Boron

SilicaSlide15

Flavinoids

found in red, blue, purple berries, red and purple grapes and Red wine.Flavanols found in teas (green, black and oolong white), chocolate (choose dark chocolate for lower sugar content and higher

catechin

content!), grapes, berries and apples.

Proanthocyanidins

found in chocolate, apples, berries, red grapes and red wine.Slide16

Flavanones found in Citrus.

Flavonols found in yellow onions, scallions, kale, broccoli, apples, berries and teas.Flavonesfound

in parsley, thyme, celery, and hot peppers.

Isoflavones

found in Soybeans Legumes.

Non-flavonoid Polyphenols found in

Tumeric.Resveratrol found in Grapes.Slide17

Phenolic acids or Phenolic

diterpenes found in Rosemary.Organosulfur compounds found in Cruciferous or Brassica vegetables - Sprouts of Broccoli & Cauliflower (highest content), kale, broccoli,

brussel

sprouts, cabbage, cauliflower,

bok

choy, collards, Chinese broccoli and Broccoli

rabe, kohl rabi, mustard, turnip, radish, arugula and watercress.Thiosulfonate found in Garlic - Aged garlic is fermented garlic that converts allicin

to S-

allylcysteine

& S-

allylmercaptocysteine

, which are more bioavailable, water soluble and stable.

Cinnaminic

aldehyde found in Cinnamon.Slide18

Nutrigenomics and Healing DeficitSlide19

Critical role of non-essential nutrients

The cell and organ systems have a natural ability to detoxify, self-destruct and regenerateinnate

healing functions – epigenetic and nutrigenomic

The body has a natural direction of cure

Can we, through nutrition (nutrigenomics), not only homeopathy, we can change the vital force and follow Herring’s Law.Slide20
Slide21

Questions/Answers: What are the three common Drug-Nutrient Interactions in which nutrient priority could preempt death?

Diuretics (Loop and Thiazide) and Magnesium/Potassium

Acetaminophen and Glutathione/NAC

Coumadin and Vitamin K

Identify 3 mechanisms by which pharmaceutical prescriptions create healing deficit?

Deplete essential nutrientschange normal standards to favor pharmaceutical prescriptionobstruct balanced intakeimpede healthy gene expression leading to toxicity

mass medical misunderstanding of nutritional implications

What medications downregulate NrF2 expression?

It’s a cellular

chemoprotective

pathway that controls programmed cell death, methylation and cell detox. Expression of NrF2 is turned on by certain nutrients that increase cells production of inborn antioxidant systems such as melatonin, glutathione, catalase and superoxide dismutase.