PPT-Evolution of new protein topologies through multistep gene

Sergio G Peisajovich Liat Rockah amp Dan S Tawfik Introduction Protein Folds Protein folding  is the process by which a protein structure assumes its functional shape or conformation It is the physical process by which a polypeptide folds into its characteristic and functional threedimensional structure from random coil. How to Identify Multistep Equations |Combining Terms| How to Solve Multistep Equations | Consecutive Integers | Multistep Inequalities. Learning Objectives. Use the properties of equality to solve multistep equations of one unknown. Interactions. June 18, 2015. Why PPI?. Protein-protein interactions determine outcome of most cellular processes. Proteins which are close homologues often interact in the same way. Protein-protein interactions place evolutionary constraints on protein sequence and structural divergence. Ben Spoerlein. Resident Assistant. Ball State University. Muncie, IN. Charles Darwin. (February 12. th. , 1809 – April 19. th. , 1882). Credited with providing the first convincing evidence for the theory of evolution in his immortal work, . Tonya C. Bates. Erin Dolan. Meredith S. Norris. John Rose. Tarren Shaw. Suann Yang. Ron Zimmerman. Facilitators: Kelly Hogan and Jennifer Warner. Gene Expression. Topic: Genetic Regulation. Context: Large lecture section of introductory biology students . The DNA inherited by organisms leads to specific traits by dictating synthesis of proteins . The process by which DNA directs protein synthesis is called . Gene Expression. Transcription. Translation. DARWIN’S UNDERSTANDING VS. PRESENT DAY. How are inheritable traits passed?. How do variations appear?. Today’s understanding of genes, DNA, variation, and mutations is central to our understanding of how evolution works . Summary of Research Interests. Gene identification and genome annotation. The evolution of genome-sequence compositional properties. Models of protein evolution. The phylogeny of Bacteria. Measures of differentiation from genomic and . Copyright 2016 by the Rector and Visitors of the University of Virginia Nucleus DNA RNA Cytoplasm Step 1 : Deoxyribonucleic acid (DNA) is stored within the compartment of the cell called the nucleus. Answer in writing: . what is DNA? Where is yours? . A . very long macromolecules that contains your genetic material. It’s found in the nucleus of each one of your cells.. A segment of DNA which codes for a protein, which determines a trait.. Lecture Presentation by . Nicole . Tunbridge. and. Kathleen Fitzpatrick. Reading the Leaves from the Tree of Life. Complete genome sequences exist for a human, chimpanzee, . E. coli. , brewer. ’. s yeast, corn, fruit fly, house mouse, rhesus macaque, and many other organisms. A trait that improves a population’s reproductive success is . an adaptation. .. An individual/population that is . adapted. is successful at producing grandchildren in its environment.. Adaptation. Prediction . Wang Yang. 2014.1.3. Outline. Molecular. . Co-evolution . phenomenon. A. pplications . of Co-evolution . in . protein structure prediction and PPI prediction.. Co-evolution measurement: . Origins of Life on Earth. 4.7-4.8 Billion Year History. Evidence from chemical analysis and measurements of radioactive elements in primitive rocks and fossils. . Life developed over two main phases:. lacZ . b. -galactosidase histochemical test yes animal. GUS. . b. -glucuronidase histochemical test yes plant. GFP Green Fluorescent Protein fluorescence no animal/plant.