PPT-Oxidative Phosphorylation

Pratt and Cornely Chapter 15 Goal ATP Synthesis Overview Redox reactions Electron transport chain Proton gradient ATP synthesis Shuttles Standard Reduction Potential potential to be reduced. Lecture . 14. Energy from Reduced Fuels is Used to Synthesize ATP in Animals. Carbohydrates, lipids, and amino acids are the main . reduced fuels. for the cell. Electrons from reduced fuels used to reduce NAD. 11 . Slides. fig19-16. electron transport chain. fig19-17. proton-motive force. 23.6 kJ/mole H. +. the coupling question…. chemiosmotic hypothesis!. the coupling question…. chemiosmotic hypothesis!. Ken Wu. Disclaimer. This tutorial is a simple and conceptual guide to metabolism. If there are any conflicts between my slides and the lecturers, . THE LECTURER IS ALWAYS RIGHT…. …maybe not always but they set your exams so if in doubt, refer back to their teaching. & . Elimination. Dr. Sandro Percario. Editorial . Board Member. Professor. Ph.D., Federal University of . Para, Brazil. Guest Researcher. US Centers for Disease Control and Prevention, . USA. .. Oxidative Stress. O. 2. is readily reduced to form one of many Reactive Oxygen Species (ROS) . ROS cause cellular damage. DNA. Protein. Lipids. http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/ros.gif. The flow of electrons from NADH and FADH. 2. to O. 2. occurs in the electron-transport chain or respiratory chain.. This exergonic set of oxidation–reduction reactions generates a proton gradient.. Pratt and . Cornely. , Chapter 15. Goal: ATP Synthesis . Overview. Redox reactions. Electron transport chain. Proton gradient. ATP synthesis. Shuttles. Analogy: How does burning coal put flour in the grocery store?. P. hosphorylation. Sites to. . K. inases. . by Conditional Random Fields. --- . CS 104 Project. Lu He, . Tuobin. . W. ang . Background and Problem. Problem: . Given . groups of . kinases. Anju. .M.P. BCH.10.05.12. One of the paradoxes of life on this planet is that the molecule that sustains aerobic life, oxygen, is not only fundamentally essential for energy metabolism and respiration, but it has been implicated in many diseases and degenerative conditions. Objectives: Oxidative Decarboxylation. By the end of this lecture, students are expected to:. Recognize the various fates of pyruvate. Define the conversion of pyruvate to acetyl CoA. Discuss the major regulatory mechanisms for PDH complex. Dr. Sandro Percario. Editorial . Board Member. Professor. Ph.D., Federal University of . Para, Brazil. Guest Researcher. US Centers for Disease Control and Prevention, . USA. .. Biography. Sandro Percario Graduated in Biological Sciences - Medical . (mitochondria and . peroxisomes. ). Dr. Mamoun Ahram. Faculty of Medicine. Second year, Second semester, 2014-2014. Principles of Genetics and Molecular Biology. What are the mitochondria?. Mitochondria are thought to have evolved from bacteria via . Citric Acid Cycle. Only a Small Amount of Energy Available in Glucose is Captured in Glycolysis. 2. G’° = -146 kJ/mol. Glycolysis. Full oxidation (+ 6 O. 2. ). G’° = -2,840 kJ/mol. 6 CO. 2. Departments of Biochemistry and Neurology. Alzheimer’s Disease Research Center. Emory University, School of Medicine. Brain . phosphoproteome. network analysis discriminates Alzheimer’s Disease from other .