PPT-Abnormal Liver Function Tests

Dr Heather Lewis Consultant Hepatologist Imperial College Healthcare NHS Trust The Lancet 2014 Mortality from liver disease in the UK Liver function tests vs liver blood tests Bilirubin albumin and INR are the only blood markers of liver function. Jon . Bishop. Consultant Paediatric Gastroenterology. Starship Children’s Hospital. CF Liver Disease. Single . commonest non-respiratory cause of CF mortality. Various manifestations. Neonatal cholestasis. Pb. Emmanuel Obeng-Gyasi MPH, Ph.D.. Source—National . Institutes of Health . Background: Lead in gasoline. Major Source of Lead exposure. Belief . lead had the ability to boost engine performance by:. Measurement of Serum Bilirubin (Total, direct &indirect) . T.A. Bahiya Osrah. Bilirubin. Bilirubin. is the product of . heme. degradation (80% hemoglobin, 20% other . hemo. -protein as . cytochrome. ALT&AST . T.A. Bahiya M. Osrah. Liver Functions. The liver is in the upper right part of the abdomen. . The functions of the liver include: . 1-storing glycogen (fuel for the body) which is made from sugars. . . . 1. .Metabolic Functions. :. U. rea cycle. Glycogen synthesis. Vitamin Metabolism. Minral Metabolism. Lipid Metabolism. Glycolysis. . . 2. .Excretory Functions. :. Cholesterol. Bile Pigments. William Alazawi MA(. Cantab. ) PhD MRCP. Senior Lecturer and Consultant in . Hepatology. Queen Mary, University of London. Does Liver Disease Matter?. Mortality in England & Wales. Liver-related mortality in under 65s. . . Shaimaa. . Munther. . Basic Anatomy. • liver unequally divided. into 2 lobes. • it has a dual blood supply. – Portal vein. – Hepatic artery. It has an excretory system for bile excretion. human and mouse liver morphology . Nissi Varki. UC San Diego. A few examples of normal and abnormal human and mouse liver morphology . 1. A few examples of normal and abnormal human and mouse liver morphology . CRMS (CF related metabolic syndrome). CFRD (diabetes). CFRLD (Liver disease). PS (pancreatic sufficient). PI (pancreatic insufficient). 1981 average age: 18. 2016 average age: 39 (oldest 86). Not just a pediatric illness. DATASET VARIABLE DATA TYPE REFERENCE RANGE UNITS Lab_tests SID Unique Subject Identifier character Lab_tests DATEBCOL Blood collection date in format of mm/dd/yy character Lab_tests TIMEBCOL Blood col An 8-year-old boy presents with three days history of abdominal pain lasting ~20 min. It occurs before breakfast & sometimes at school, where it will generally pass when . . he busies himself with activities. He has a tendency to constipation. His pains worsen when faced with tests at school or other stressors. Exam is normal. Julia Gore Thornton MD, MPH. Staff Gastroenterologist. Summa Health Medical Center. Borderline and Mild Elevation of Liver Tests. American Journal of Gastroenterology Jan 2017. Formal review and literature search. Each organ of the body has to perform its biochemical functions. Possible only when the cells of the organ are intact in structure and function. Any abnormality in the tissue caused by exogenous or endogenous factors will seriously impair the organ function which influences the health of the organism. DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). Objectives :. At the end of this lecture, the student should know:. What is DILI?. What are the different pattern of DILI?.