PPT-Chromatin Remodeling Complexes in Heart Valve development

Maithri Sarangam Summer 2012 Stankunas Lab BAF Chromatin remodeling complex Heart Valves Significance Congenital heart valve defects affect significant portion of the world population . stenosis. , regurgitation, . prolapse. , bacterial infection, aneurysm and . Tetralogy. of . Fallot. . . HOWEVER, DID YOU KNOW? In a recent survey, most heart valve surgery patients stated that their expectations were "mismanaged - both before and after surgery.”. The Pathway of the Blood. Through the heart, beginning at the vena cava. anterior (inferior) vena cava is at the bottom. superior vena cava is at the top. blue blood (deoxygenated) enters the right atrium. trithorax. -Group (. trxG. ). Maintain the “on” state of developmental regulatory genes. trx. : founding member (HMT on H3K4). . Transcriptional memory by . trxG. and . PcG. trxG. – on state memory. The Electrocardiogram. . The conduction of APs through the heart generates electrical currents that can be read through the skin. AP = Action Potential. Currents picked up by electrodes. The recording is called an . Heart Anatomy. Approximately the size of a fist. Location. In the mediastinum between second rib and fifth intercostal space. On the superior surface of diaphragm. Two-thirds to the left of the midsternal line. Carpentier. -Edwards pericardial bioprosthesis in patients with rheumatic heart disease aged below 40 years: 17-year results. Chowdhury UK . et al. Heart Lung Circ. . 2018; . 27. : 864–71.. Study details. ♦ An average adult human contains. about 5 liters (5.3qt) of blood.. ♦ The blood makes up about . onethirteenth. of the body’s weight.. ♦ The adult heart weighs about 280 grams (10 oz.). ♦ At rest, the heart pumps out about 80 millimeters. By: Group . 3. Ratih Anggraeni. Sri Restutik. Suis Priyati. Tuhfatul Laily. WALL OF HEART. Epicardium. Myocardium. Endocardium. . The human heart is four chambered. The upper chambers are called the atria or the auricles and the lower two chambers are called the ventricles. The two atria are separated by the . is . about . the . size of a . fist.. Located in the . mediastinum. (space between lungs, backbone, sternum. ).. The distal end of the heart is called the . apex. .. Sagittal view of the thoracic cavity, lung removed. . Genome in eukaryotes is large enough to be accommodated in tiny nucleus. It is required to achieve high degree of compaction for getting into the nucleus. Compaction is achieved by folding the DNA in ZOO LOGY Cell Biology Cell Regulatory Mechanisms : Chromatin Remodeling 1 Development Team Paper Coordinat or: Prof. Kuldeep K. Sharma Department of Zoology, University of Jammu Principal Investigat Tricuspid Valves Cardiac Surgery - MATRIx Program - 1 - Heart anatomy The heart has two sides, separated by an inner wall called the septum . The right side of the heart pumps blood to the lungs to . features. .. Structure . of heart wall, myocardium, . valves. , . anuli. fibrosi . Dr. Altdorfer. Structure of heart . wall. Pericardal. . sack. Epicardium. Pericardium. Fibrous. . skeleton. (. heart . valve prosthesis in a multicenter study on patients undergoing open heart valve surgery . Principal investigator:. Dr. Gholamreza Omrani. F. reely . floating valve . leaflets, CardiaMed. Rationale.