Child and Adolescent Psychiatry Fellow Institute for Juvenile Research University of Illinois at Chicago Objectives Review basic concepts and epidemiology of child maltreatment Discuss psychiatric diagnostic issues in abused or neglected children ID: 670674
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Slide1
Child Abuse and Neglect
Shannon Wagner Simmons, MD, MPH
Child and Adolescent Psychiatry Fellow
Institute for Juvenile Research
University of Illinois at ChicagoSlide2
Objectives
Review basic concepts and epidemiology of child maltreatment
Discuss psychiatric diagnostic issues in abused or neglected children
Provide an overview of the treatment of PTSD in children and adolescents, including a brief review of the psychopharmacology literature
Discuss a clinical exampleSlide3
Jane
Jane is a 15 year old girl with a history of a learning disorder who presents to an outpatient intake clinic with a two-month history of generalized anxiety and panic attacks.
She had no prior psychiatric history.
Medical history includes only mild asthma.
Birth, developmental, and family histories are noncontributory.
She has a younger sister who lives at home; parents are divorced.Slide4
Jane, continued
She began weekly CBT with a psychology intern.
In the fourth session, she disclosed to her therapist that she had been repeatedly raped by a family friend in her home over the summer.
This family friend still visits the home often.
“I’m
not
ready to tell my mom.”
Jane admits that she has been smoking marijuana several times weekly to manage her anxiety symptoms.
She also endorses nightmares, flashbacks, and hypervigilance. Slide5
Jane – A Few Questions
If you were the therapist, what would you do next? What are you worried about?
Why did she disclose this now?
How would this information change your treatment approach?Slide6
Some Numbers
3 million suspected cases reported annually
1 million of these are substantiated
60% neglect, 20% physical abuse, 10% sexual abuse, 10% miscellaneous
Lifetime incidence of maltreatment:
30% in child psychiatry outpatient populations
55% in child psychiatry inpatient populationsSlide7
Some Definitions
Physical Abuse: “Intentional injury of a child by a caretaker…that lead[s] to injury, and frequently occurs in the context of discipline.”
Neglect: “Caretakers fail to appropriately provide for and protect children…failing to meet the child’s nutritional, supervision, or medical needs.”
From
Lewis’s Child and Adolescent Psychiatry: A Comprehensive TextbookSlide8
Some Definitions
Sexual Abuse: “Sexual behavior between a child and an adult or two children when one of them is significantly older or uses coercion…may include exhibitionism”
Psychological Abuse: “When an adult repeatedly conveys to a child that he is worthless, defective, unloved, or unwanted…it may involve threatened or actual abandonment.”
From
Lewis’s Child and Adolescent Psychiatry: A Comprehensive TextbookSlide9
Child Risk Factors for Abuse
Prematurity
Age under 4 years
“Special Needs”
Disruptive behaviorSlide10
Caregiver/Family Risk Factors for Abuse
Poverty
Substance Abuse
Domestic Violence
Caregiver history of being abused
Transient nonrelated caregivers
Social stressorsSlide11
Psychiatric Sequelae
Maltreated children are at risk for:
Attachment disorders
Social/peer relationship problems
Language delays
Below-average standardized test scores
Intimate Partner Violence
Teen parenthood
Perpetrating abuse
Age-inappropriate sexual behavior
Mood disorders
Anxiety disorders
Psychosis
Alcohol and drug abuse
Eating disorders
Disruptive behavior
Borderline personality disorder
Dissociative disordersSlide12
Predictors of More Favorable Long-Term Outcomes
Consistent support system after the trauma
Limited relationship with perpetrator
Some genetic polymorphisms:
5HTTLPR (Serotonin Transporter Gene) and depression
CRHR1 (
Corticotropin
-releasing hormone receptor)
MAO-A (monoamine oxidase-A) and aggression
Catechol-O-
methyltransferase
(COMT) Slide13
Diagnostic Issues
“Single-blow” vs. chronic trauma
Neglect vs. physical abuse
Internalizing vs. externalizing
“Complex Trauma”Slide14
Diagnostic Evaluation
Maltreated children are at risk for a wide range of psychopathology.
Developmental state at the time of trauma and at presentation is key.
A thorough diagnostic assessment is indicated.
We must ask the questions
, sometimes several times.
Mandated reporting issuesSlide15
PTSD
Three symptom clusters: re-experiencing, avoidant, and hyperarousal
Some DSM criteria allow for developmental differences, but others do not.
There is some controversy about how accurately these criteria capture the disorder in children, especially young childrenSlide16
PTSD Screening Tools
UCLA PTSD index
Trauma Symptom Checklist
Anxiety Disorder Interview Schedule (ADIS) PTSD section
Others
Sometimes children report things on rating scales that they do not report verbally.Slide17
Treatment Planning
The treatment should be tailored to the symptoms/disorder.
Safety First: Be vigilant for ongoing maltreatment or re-traumatization
Treatment often requires working with a larger multidisciplinary team and focusing on family and environmental factorsSlide18
Trauma Focused CBT
Considered best practice for children or teens who have experienced trauma
Intervenes with both the child and caregivers
Psychoeducation
, relaxation skills, affective modulation, cognitive coping related to the trauma
Creation of a trauma narrative
Free web training: http://tfcbt.musc.edu/Slide19
Pharmacotherapy of PTSD
Indications:
Severe symptoms
Suboptimal response to psychotherapy
Comorbidity with a disorder amenable to pharmacotherapy (e.g. MDD)
Combined approach (therapy + meds) is idealSlide20
SSRIs in Pediatric PTSD
Double-blind, placebo-controlled RCT: sertraline was comparable to placebo (Robb et al, 2010)
Addition of placebo or citalopram to TF-CBT: no additional benefit in treatment group (Cohen et al, 2007)
Open trial of citalopram in 8 patients: improvements seen (
Seedat
et al, 1999).
That’s all!Slide21
SSRIs: Things to Consider
Black-box warning regarding suicidal ideation
Children, especially those with severe mood dysregulation, may find SSRIs too activating
The other usual side effects
Start low, go slowSlide22
Other Agents in PTSD:Adrenergic Agents
Clonidine
reduced some PTSD symptoms in a small open trial of preschoolers (Harmon and Riggs, 1996).
Guanfacine
reduced nightmares in a case report involving a 7 year old (
Horrigan
, 1996).
Prazosin
reduced nightmares and hyperarousal in two adolescent case reports (Strawn et al, 2009;
Fraleigh
et al, 2009)
Propranolol
reduced PTSD symptoms in 11 school-aged children (
Famularo
et al, 1988)Slide23
Other Agents in PTSD: Atypical Antipsychotics
Risperidone
reduced hypervigilance and aggression in a teen (
Keeshin
and Strawn, 2009).
When added to
escitalopram
,
aripiprazole
decreased nightmares in a teen (
Yeh
et al, 2010).
Quetiapine
decreased dissociation, anxiety, and depression in a series of 6 teens with PTSD (
Stathis
et al, 2005).
Clozapine
reduced aggression and improved sleep in a case series of six treatment-resistant teensSlide24
Other agents in PTSD: Mood Stabilizers
Divalproex sodium
caused a greater reduction of PTSD symptoms when given in high vs. low doses in 12 juvenile-detention teens (Steiner et al, 2007).
In a case series of 28 children and teens with severe abuse history, most responded very well to
carbamazepine
(
Looff
et al, 1995).Slide25
Jane Revisited –
A Few Questions
If you were the therapist, what would you do next? What are you worried about?
Why did she disclose this now?
How would this information change your treatment approach?Slide26
Useful Websites
www.nctsn.org
(National Child Traumatic Stress Network)
www.aacap.org
(American Academy of Child and Adolescent Psychiatry)
Facts for Families
Practice Parameters
http://tfcbt.musc.edu/
(Trauma-Focused CBT)