PPT-Dopamine, Motivation and Schizophrenia: Research with Roden

Department of Psychology Program in Neuroscience John D Salamone PhD CNRTRICS 2010 RO1MH78023 RO1NS047261 DA009158 BACKGROUND DA and Schizophrenia Strong and Weak Forms of the DA Hypothesis. Interest in dopamine was intensified by the realisation that dopamine had an important role in the pathogenesis or drug treatment of certain brain History diseases eg Parkinsons disease schizophrenia This lead to much research on the sites of action A command and control center for our simultaneous multiple constraint satisfying machine. . Outline. Staying alive and maintaining Homeostasis. P. erception. Motivation and Effort. Emotions & Habits. From the Johns Hopkins Clinical Schizophrenia Program: Russell L. Margolis, M.D.. Krista Baker, LCPC. Tom Sedlak, M.D., Ph.D.. For information about clinical services, contact Krista Baker, 410-550-0137. Dr. Stephen M. Stahl. 1. LAT500-15 revised November 2015. Learning Objectives. To learn about neuroregulation of schizophrenia . symptomatology. . To understand current hypotheses of schizophrenia and how they influence treatment. Ms. . Carmelitano. Acetylcholine. First Neurotransmitter to be identified and most common in the human body. Function: . Helps control muscle contraction. Plays a role in the development of memory of the hippocampus. NETWORK INTERACTIONS IN SZ – THERAPEUTIC IMPLICATIONS. Awarded the Nobel Peace prize for their work on neural transmission.. Arvid. is best known for his work into the relationship between dopamine and Parkinson’s disease.. Kaushik. . Majumdar. Indian Statistical Institute. 8th Mile, Mysore Road. Bangalore 560059. https://sites.google.com/site/isicng/. Workshop on “Cognition, Emotion and Computing,” Infosys Limited, Bangalore, 30 April 2013. Dr. Stephen M. Stahl. LAT500-15 revised . February 2016. Learning Objectives. To learn about neuroregulation of schizophrenia . symptomatology. . To understand current hypotheses of schizophrenia and how they influence treatment. 2012. 1. Psychosis. Psychosis may be substance-induced or caused by brain injury, but most psychoses appear in the form of schizophrenia. Psychosis is a state defined by a loss of contact with reality. Outline. Introduction. . History . Epidemiology. Etiology . Psychosis. Severe form of mental disorder. Greater severity of illness. Lack of insight. Inability to distinguish between subjective experience and reality (hallucinations & delusions). Dopamine and It’s Uses. Neurotransmitter. Helps transmit signals in brain and other vital areas. Found in humans and animals, including vertebrates and invertebrates. Mainly inhibitory. Involved in voluntary movement, learning, arousal, and feelings of pleasure. NOT a “split personality”, a split from . reality. 1% of the U.S. population. A family of disorders, not one single disorder. Many people not diagnosed until 45. Symptoms of Schizophrenia . 1) . Introduction. Disorders on the schizophrenia spectrum. Involve psychosis, . impaired cognitive processes, . unusual or disorganized motor behavior, . social withdrawal. Symptoms of Schizophrenia Spectrum Disorders. “... a psychiatric disorder, falling within the scope of psychotic illnesses, meaning that the patient at some point develops symptoms that lead them to misinterpret reality.”. . (. Picchioni. & Murray, .