PPT-New Oral Anticoagulant

R2 Patcharee Seesongsom R2 Sirada Phojai Advisor AJ T a chawan J iratiwanon Scope Overview Introduction of NOACs Rivaroxaban Xarelto Dabigatran Pradaxa . How long to treat a DVT?. What do the ACCP Guidelines say?. Duration of Long-term Anticoagulant Therapy. In patients with a proximal DVT of the leg provoked by surgery, we recommend treatment with anticoagulation for 3 months over (i) treatment of a shorter period . Fawaz Altuwaijri. ACEM trainee. Introduction. Characteristics . of novel . anticoagulants. Laboratory Testing. Reversal in the bleeding patient. Introduction. Prevalence . atrial fibrillation. . 3.03 million in 2005. Definition of Anticoagulation. Therapeutic interference with the clotting mechanism of the blood . ("blood-thinning") to . prevent or treat thrombosis and embolism.. Indications of Anticoagulant Therapy. and major trauma. Dr. Tina . Biss. Consultant . Haematologist. Newcastle Hospitals NHS Foundation Trust. NTN Annual Trauma . Conference. 17. th. April 2015. Case history. 73 year old female . Anticoagulated. Lanae Fox, . PharmD. , BCPS. I have no financial disclosures to report. Objectives. Understand the relative benefits and limitations of oral anticoagulant options. Recognize strategies for optimal use of oral anticoagulants and minimize risk of bleeding with these agents. This presentation is based on the . December 2013. AHRQ WebM&M Spotlight Case. See the full article at . http://webmm.ahrq.gov. . CME credit is available. Commentary by: . Margaret . C. Fang. , MD, MPH, University of California, San Francisco. Dr. . Versha. Prasad. Anticoagulants Used In the Hematology Laboratory. Anticoagulants are defined as substances which prevent blood clotting / coagulation, and allow separation of the blood into cellular and liquid (plasma) components. Generally plasma contains coagulation factors. . :. are additives that inhibit clotting of blood and/or plasma. They act either by binding calcium ions or by inhibiting thrombin activity. . Platelets and coagulation factors are activated when blood vessels are punctured, and their activation continues in sample containers that do not contain anticoagulant, leads to clot formation which interfere with many analytical tests.. Patients with anticoagulant. (n=37). R-CHOP,. . n (%). 156 (51.0). 14 (37.8). R-CEOP, . n (%). 68 (22.2). 7 (18.9). R-CHOEP, . n (%). 47 (15.3). 2 (5.4). R-CVOP, . n (%). 11 (3.6). 10 (27.0). R-mini-CHOP, . existing clots from growing larger. Although anticoagulants are sometimes called blood thinners , they do not actually thin the blood. The job of anticoagulants is to promote the smooth flow of bloo Presented by-. Dr. Varun Mittal, PG. Dept of Maxillofacial Surgery. SRM DENTAL COLLEGE, CHENNAI, INDIA. Which all patients?. Mostly cardiac or vascular disorders:. Atrial. fibrillation. Ischemic cardiac disease. 1. Contact haematologist on call. , document DOAC taken and last time drug ingested, . calculate creatinine clearance (Cockcroft Gault), FBC and check INR/APTT/thrombin time. Dabigatran. Rivaroxaban. Christopher B. Granger, MD. On behalf of the IMPACT-AF . Steering. Committee and Investigators. Background. AF is common (34 million people worldwide). AF is associated with a 5-fold increased risk of stroke. Josh Smith. Overview. Adverse Drug Reactions. Toxicities. Adverse Drug Reaction. Type A Adverse drug reaction. Dose dependent . Preventable. Type B ADR. Idiosyncratic. Multifactorial. Underlying disease (kidney or liver dysfunction).