PPT-Succinic Semialdehyde Dehydrogenase Deficiency (SSADH)

Symposium March 31 2016 Inborn Errors of Metabolism Metabolomics Gerard T Berry MD Professor of Pediatrics Harvard Medical School Director Metabolism Program Boston Childrens Hospital. M. G. 1. G. 2. S. Start. here. Induce!. Induce!. Induce!. Revert!. Revert!. Revert!. Horizontal Transfer. Induce!. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Pick. Dehydrogenase. . (G-6-PD). Introduction. G6PD deficiency is an allelic abnormality which is inherited in an X-linked recessive fashion.. G6PD deficiency is also known as "favism" since G6PD deficient individuals are also sometimes allergic to . Under aerobic conditions, pyruvate enters the mitochondria where it is converted into acetyl CoA.. Acetyl CoA is the fuel for the citric acid cycle, which processes the two carbon acetyl unit to two molecules of CO. Deficiency. (G6PDD). The . glycolytic. pathway . is the main source of energy (ATP). The . hexose. monophosphate ‘shunt’ pathway. . provides the main source of reduced . nicotinamide. adenine . Adrian . Bumstead. , Xiao Qi Li, Jessica So, Jin (Donna) Yang. PHM142 Fall . 2015. Instructor: Dr. Jeffrey Henderson. Arsenic (As). Toxic metalloid. Arsenite. (. As. 2. O. 3. ; As . III). Arsenate. . Presentation to the Sustainable Chemistry Alliance. Mike Hartmann, Executive VP. June 12. 2012. Immediate access to commercial . s. cale building blocks. 3. -. 3. -. Plasticizers. Deicers. Coatings. Lecture Date :- 6-8-2018. Done By :- Saeed Karajah. Edited By :- . Ahmad . Dabbour. Doctor :- Nabil . Amer. . If you come by any mistake (whether it be spelling, grammatical or scientific) while browsing this sheet, kindly report it to the academic team . Adrian . Bumstead. , Xiao Qi Li, Jessica So, Jin (Donna) Yang. PHM142 Fall . 2015. Instructor: Dr. Jeffrey Henderson. Arsenic (As). Toxic metalloid. Arsenite. (. As. 2. O. 3. ; As . III). Arsenate. Dr. Delma D’Cunha. 1. , Dr. Balakrishna P.S.. 2. , Dr Priya Mitali. 3. , Dr Kishan Shetty. 4. 1. Post graduate Resident, . 2. Assistant Professor, . 3. Senior Resident, . 4. Associate Professor. Department of Anaesthesiology. M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. In . the TCA cycle, oxaloacetate is first condensed with an acetyl group from acetyl CoA, and then is regenerated as the cycle is completed . Principle . Glucose 6 p + NADP. +. G6PDH gluconate 6P+NADPH+ H. +. NADPH will florescence under UV light if there is deficiency of enzyme . NO. florescence will appear. .. G6PDH= glucose 6 phosphate dehydrogenase. Elevated C8 with Lesser Elevations of C6 and C10 AcylcarnitineMediumChain AcylCoA Dehydrogenase Deficiency (MCAD)Differential Diagnosis: Mediumchain acylCoA dehydrogenase deficiency (MCAD). MediumChai succinic. acid. Theory: . Consider a system consisting of two liquid layers (phases) of two immiscible or slightly miscible liquid. If a third substance ,. Which is soluble in both liquids, is added into the system it is found to distribute ,or divide, itself between the two layer in a definite manner .It has been shown experimentally that at equilibrium, at constant temperature ,the ratio of the concentrations in the layers has a definite value. If C1 and C2 are the concentrations of this substance in two layers ,then:. dinucleotide. . binding. . proteins. Blanca . Risa. Gemma Serra. Xaloc . Téllez. Anna . Troya. CURS 2013- 2014 . GRAU EN BIOLOGIA HUMANA. Introduction. Enzymes. . that. . bind. . nucleotides. NAD(P) – NAD(P)H.