Principle Glucose 6 p NADP G6PDH gluconate 6PNADPH H NADPH will florescence under UV light if there is deficiency of enzyme NO florescence will appear G6PDH glucose 6 phosphate dehydrogenase ID: 920369
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Slide1
lab 9G6PD
Daheeya
AlEnazi
Slide2Principle
Glucose 6 p + NADP+
G6PDH gluconate 6P+NADPH+ H
+
NADPH will florescence under UV light if there is deficiency of enzyme NO florescence will appear.G6PDH= glucose 6 phosphate dehydrogenase
Slide3Clinical significant
G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose-6-phosphate dehydrogenase, which helps RBCs function normally.
This deficiency can cause
hemolytic anemia
, usually after exposure to certain medications, foods, or infections.Most people with G6PD deficiency don't have any symptoms, while others develop symptoms of anemia only after RBCs have been destroyed, a condition called hemolysis. In these cases, the symptoms disappear once the cause, or trigger, is removed. In rare cases, G6PD deficiency leads to chronic anemia
Slide4Causes of G6PD Deficiency:
G6PD deficiency is passed along in genes from one or both parents to a child.
The gene responsible for this deficiency is on the X chromosome
Sample:
will be whole blood.
Slide5Result under UV light
Normal
Deficient