PPT-Biochemistry Lec:7 Dr.Radhwan

M Asal Bsc Pharmacy MSC PhD Clinical Biochemistry Gluconeogenesis SUBSTRATES FOR GLUCONEOGENESIS Gluconeogenic precursors are molecules that can be used to produce a net synthesis of glucose They include all the intermediates of glycolysis and the citric acid cycle Glycerol lactate and the α. Dr. . Kerith. Golden. Biochemical Sciences at Mona. Department of Basic Medical Sciences. Biochemistry. Anatomy. Physiology. Pharmacology. Physical Therapy. Dentistry. Degrees offered: . BSc. , . MPhil. NBME . Subject and . USMLE . Step Exam Observations from Writers and Reviewers. Janet Lindsley, PhD & Eric . Niederhoffer. , PhD. . Discussion outline. Introduction to the NBME & USMLE. Roles of Test Development and Interdisciplinary Review Committees. INTRODUCTION. Biochemistry . Biochemistry. is the application of chemistry to study biological processes at the cellular and molecular level.. Biochemistry is also concerned with the study of the structure and function of cellular components, such as proteins, carbohydrates and lipids.. 1. What is Biochemistry?. Biochemistry = chemistry of life. . Biochemists use physical and chemical principles to explain biology at the molecular level.. Basic principles of biochemistry are common to all living organism. M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. Bioenergetics and Oxidative Phosphorylation. . Bioenergetics . describes the transfer and utilization of energy in biologic systems . M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. Glycogen Metabolism . The . main stores of glycogen in the body are found in skeletal muscle and liver, although most other cells store small amounts of glycogen . M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. GLYCOLYSIS. REACTIONS . OF GLYCOLYSIS . The conversion of glucose to pyruvate occurs in two stages . ,The . first five reactions of glycolysis correspond to an energy investment phase in which the phosphorylated forms of intermediates are . M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. In . the TCA cycle, oxaloacetate is first condensed with an acetyl group from acetyl CoA, and then is regenerated as the cycle is completed . Bsc. . Pharmacy. MSC . ,PhD Clinical Biochemistry. Nutrition, . Digestion, & Absorption. BIOMEDICAL IMPORTANCE. Besides water, the diet must provide metabolic . fuels (mainly . carbohydrates and lipids), protein (for . M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. ELECTRON TRANSPORT CHAIN . The electron transport chain is present in the . inner mitochondrial membrane . and is the final common pathway by which electrons derived from different fuels of the body flow to oxygen. Although . Kerith. Golden. Biochemical Sciences at Mona. Department of Basic Medical Sciences. Biochemistry. Anatomy. Physiology. Pharmacology. Physical Therapy. Dentistry. Degrees offered: . BSc. , . MPhil. , PhD. Bsc. . Pharmacy. MSC . ,PhD Clinical Biochemistry. Lipids. The . lipids are a heterogeneous group of . compounds, including . fats, oils, steroids, waxes, and related . compounds, which . are related more by their physical . M. . Asal. Bsc. . Pharmacy. MSC ,PhD Clinical . Biochemistry. STRUCTURE OF FATTY ACIDS. A . fatty acid consists of a hydrophobic hydrocarbon chain with a terminal carboxyl group . , At . physiologic pH, the terminal carboxyl group . Slides to accompany Organic and Biochemistry Supplement to Enhanced Introductory College Chemistry by Gregory Anderson, Jen Booth, Caryn Fahey, Adrienne Richards, Samantha Sullivan Sauer, and David Wegman.