PPT-The Basics of Cancer Biology

Lucio Miele MD PhD The Basics of Cancer Biology With special thanks to Andrew Hollenbach PhD Wanguo Liu PhD Antonio Pannuti PhD For providing original materials Course outline The Selfish Cell Darwin and Cancer. Cancer Informatics (omics). David Boone. Outline. What is cancer and how is it different from other diseases?. Major players in tumor initiation (Understand one before many) . Oncogenes. Tumor suppressors. Lucio Miele, M.D., Ph.D.. Part III: “The Pianist and the Piano”. Bad music, . stem cells and . bad luck. The genetic piano. The genetic piano - 2. Our genomes can be compared to piano keyboards, where each key is a gene. Cancer Informatics (omics). David Boone. Outline. What is cancer and how is it different from other diseases?. Major players in tumor initiation (Understand one before many) . Oncogenes. Tumor suppressors. Lucio Miele, M.D., Ph.D.. Part III: “The Godfather and the Untouchables”. How cancer cells avoid and corrupt the police – and what to do about it. A Primer on Cancer Immunology. http://. bcove.me/1xr0xjty. Richard H. Lathrop. Dept. of Computer . Science. Univ. of California, Irvine. rickl@uci.edu. Donald Bren Hall 4224. 949-824-4021. “Computers are to Biology as Mathematics is to Physics.”. --- Harold . Emerging Clinical Applications. Mahmood rasheed. Hematology/oncology fellow. VCU Massey Cancer Center. Extracellular Vesicles. Heterogenous range of particles shed from virtually all cells in the human body.. (© Garland Science 2007). Cell Cycle Checkpoints. The Guardian Mechanisms of . the Genome. THEY ARE DISRUPTED. IN CANCER!. Entering Mitosis Before the Completion of S phase is. Bad for Chromosomes and Therefore Bad for Cells . PATHG4500 Fall 2019. Introduction. Recommended Textbook . The Biology of CANCER. Robert A. Weinberg. Second Edition. Cancer Biology PATHG4500-001. Meets on select Mondays and Wednesdays. Course Directors: Anna . Julie R. Gralow, M.D.. Director, Breast Medical Oncology. Jill Bennett Endowed Professor of Breast Cancer. Professor, Global Health. University of Washington School of Medicine. Fred Hutchinson Cancer Research Center. 2018-2019 MOLECULAR ONCOLOGY AND TUMOR IMMUNOLOGY TRAINING PROGRAM DEPARTMENT OF PATHOLOGY 550 First Avenue Medical Sciences Building, 5th Floor New York, NY 10016 molecular-oncology-and-immunology C Oncology Patient Navigator Training: The Fundamentals. Acknowledgements. This work was supported by Cooperative Agreement #1U38DP004972-02 from the Centers for Disease Control and Prevention. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention.. Cancer Grand Challenges. Open for applications. Founded by:. 9 challenges | £20m awards | apply today . Cancer Grand Challenges: a global funding platform to solve the toughest problems in cancer research, founded by Cancer Research UK and the US National Cancer Institute. is disease characterized by uncontrolled cell growth. . Characteristics of Cancer Cells:. 1. ) Lack of Differentiation . . Differentiation. is the process of cellular development by which a cell acquires a specific structure and function. . Sylvia Plevritis, PhD. Course Director. Melissa . Ko. Teaching Assistant. Fuad. . Nijim. CCSB Program Manager. March 31, 2014. Goals of CBIO243. Introduce major principles of cancer systems biology that integrate experimental and computational biology..