PPT-HOW DO ANTIDEPRESSANTS WORK ON DEPRESSION?

Selen AK 1803337 PSYC374 Outline Introduction Definition of depression Symptoms Treatment How Serotoninamp Norephinephrine Works Types of antidepressants TCAs MAOIs SSRIs Tolerance and withdrawal symptoms. Richard C. Shelton, M.D.. James G. Blakemore Research Professor. Vice Chair for Clinical Research. Department of Psychiatry. Professor, Departments of Pharmacology and Psychology. Vanderbilt University. They are very, very common.. What are the symptoms of depression?. What are the symptoms of anxiety?. How do you treat it?. Are antidepressants stimulants or depressants?. 1. Introducing Dopamine and Serotonin. Antidepressants. Antidepressants. Primarily used to relieve symptoms of depression. Can also help patients with anxiety disorders. Not indicated for uncomplicated bereavement. Antidepressant Groups. Tricyclic antidepressants. Group 4: Chan Yong Ming, Timothy . Peh. , Bernetta . Kwek. Presenter: Bernetta . Kwek. Assigned reading. Johnson, Blair R. and Kirsch, Irving (2008). Do antidepressants work? Statistical significance versus clinical benefits. Significance 5(2), 54-58.. Antidepressants. Primarily . used. to relieve symptoms of . depression. Can also help patients with . anxiety. disorders. Not indicated for uncomplicated bereavement. Depression. Most common psychiatric disorder . Group 4: Chan Yong Ming, Timothy . Peh. , Bernetta . Kwek. Presenter: Bernetta . Kwek. Assigned reading. Johnson, Blair R. and Kirsch, Irving (2008). Do antidepressants work? Statistical significance versus clinical benefits. Significance 5(2), 54-58.. Group 4: Chan Yong Ming, Timothy . Peh. , Bernetta . Kwek. Presenter: Bernetta . Kwek. Assigned reading. Johnson, Blair R. and Kirsch, Irving (2008). Do antidepressants work? Statistical significance versus clinical benefits. Significance 5(2), 54-58.. Richard C. Shelton, M.D.. James G. Blakemore Research Professor. Vice Chair for Clinical Research. Department of Psychiatry. Professor, Departments of Pharmacology and Psychology. Vanderbilt University. Grace Davis April 19, 2011 Medicinal Chemistry CHEM 5398 Antidepressants Depression and Symptoms Foremost cause of disability as measured by years lived with a disability Affects 121 Million people worldwide Anxiolytic. Agents. History. Prior to antidepressant agent discovery in the 1950s, electroconvulsive shock was administered as well as opiates to induce euphoria in patients with anxiety. The 1950s was known as the Golden decade for the psychopharmacology industry. Nathan Kline went further to show that it had a stimulatory effect on depressed patients. . Mark Williams, MD. Why Shared Decision Tool on Antidepressants?. Depression a common and disabling problem. 10% of primary care population. Among top reasons for disability worldwide. Depression highly stigmatized and poorly defined. What are the symptoms of depression?. What are the symptoms of anxiety?. How do you treat it?. Are antidepressants stimulants or depressants?. 1. Introducing Dopamine and Serotonin. 2. DA and 5-HT. One thousand times less common than the major neurotransmitters. . SSRI’s (. fluoxetine. ) and SNRI’s (. venlaflaxine. ) are first line. treatment for most . anxiety disorders. Major (. Unipolar. ) Depression. Dysthymia . (Persistent Depressive Disorder). Bipolar Affective Disorder. depressed as they do manic/hypomanic (Baldessarini etal. ). In bipolar II patients, depression may be even more dominant. As an example, one study found a 37:1 ratio of depressive to hypomanic weeks