PPT-Randomised

C ontrolled Trials a workshop Ngaire Kerse Professor and General Practitioner and asker of questions Key issues randomised trials There must be uncertainty The question m ust be answerable and feasible. Asp irin and ticlopidine have been shown to be effective but both have potentially serious adverse effects Clopidogrel a new thienopyridine derivative similar to ticlopidine is an inhibitor of platelet aggregation induced by adenosine diphosphate Me 77 patientsregistered 68 randomised 34 assignedPT 34 assignedAT 29 completedtrial30 completedtrial111 excluded 5 withdrawn 4 withdrawn To be included in the study athletes had to be male, aged18 effective when it was not. That is to say, it does not undermine any observed association between an intervention and outcome - it makes it more believable.Can I trust this research result? Lots of s The single blind, randomised, crossover study was carried out with volunteers aged between 19 and 55. The volunteers ate one daily portion of watercress in addition to their normal diet. The key fi to increase smoking cessation by maintaining NHS Stop Smoking Service attendance FAITH MATCHAM PHD STUDENT, DEPARTMENT OF PSYCHOLOGICAL MEDICINE, IOPPN Today ◦ BACKGROUND ◦ AIM % Hawthorn, Victoria 3122. Australia. Email: gdevilly@swin.edu.au Acknowledgement: We would like to acknowledge Ms Tracey Va 1 we employed an analogue study with were shown a stressful video of parame Graeme MacLennan. James Lind. Born Edinburgh 1716. On HMS Salisbury in 1747 he allocated 12 men with scurvy. Cider. Seawater. Horseradish, mustard, garlic. Nutmeg. Elixir Vitriol . Oranges and Limes . Appraisal. “Frequency and Prevention of symptomless deep-vein thrombosis in long-haul flights: a randomised trial”. Group. . 8. Case Illustration. A Couple, Men . and women . , 55 yo want to travel with economy . Randomised trials face many challenges including slow or suboptimal recruitment;. Across trials, it is estimated that less than 50% meet their recruitment target or do so only with an extension to the original trial duration;. EMPA-REG Trial Randomised , double-blind, placebo-controlled cardiovascular outcomes trial The primary end point is the time from randomization to a composite outcome consisting of the first occurrence of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke (3 point Major Adverse Cardiovascular Events or 3-MACE) for asymptomatic severe carotid artery stenosis. . Alison Halliday. Nuffield Department of Population Health (NDPH). University of Oxford, UK . for the ACST-2 collaborators. ACST-2. is published online in . A. ccelerated, . D. ose escalated, . S. equential . C. hemo-r. a. diotherapy . in . N. on-Small Cell Lung Cancer. Rationale:. Lung cancer. is the most common cause of cancer mortality in the UK, and . testing an intervention . to. lower cardiovascular . disease risk for people with severe mental illnesses in primary . care. Alexandra Burton. Programme Manager. UCL Division of Psychiatry. Background . 2. Icahn School of Medicine at Mount Sinai, New York, United States, . 3. Hopital Tenon, Paris, France, . 4. Fundación Huesped, Buenos Aires, Argentina, . 5. AIDS Research Consortium . of Atlanta, Atlanta, United States, .