PPT-New approaches for developing viral vaccines against influenza and respiratory syncytial

SangMoo Kang Georgia State University December 8 2015 Virology2015 Atlanta 1918 H1N1 The worst and greatest pandemic deaths of 40 to 100 million people worldwide Lung inflammation. . Done by . :. . Yasmin. El . Helu. . Rana. Abu . Zuhri. . Asmaa. Abu . Shamla. Respiratory tract . infection. Fungal infection . of . the respiratory tract. Aspergillosis. . . I. s an allergic reaction, invasive infection or growth caused by . Claude MUVUNYI M.D., Ph.D.. Viral diseases. The relative susceptibility of a person and the severity of the disease depend on factors such as: . the . nature of exposure; . the . immune status, . age. Ananda. Kumar . Saha. Dept. of Zoology. Rajshahi. University . Viral Diseases. Viral. . diseases. . are structural . or . functional disorder of an organism caused . by . infection of viruses. .. Objectives. Review the New Jersey state influenza vaccination law and how it affects your healthcare facility. Discuss CDC recommendations for protecting staff and patients/residents during influenza season. Orthomyxoviridae family of viruses. RNA enveloped viruses that make up three genera. Influenzavirus A. Influenzavirus B. Influenzavirus C. The type A viruses are the most virulent among the three, genetically diverse and infecting human, birds and animals. 1. 2. RNA Viruses. Diverse group of microbes . Assigned to one of 12 families based on envelope, capsid, and nature of RNA genome. 3. Enveloped Segmented Single-Stranded RNA Viruses. Orthomyxoviruses. MD, PhD . General Consideration . Acute viral respiratory illnesses are among the most common of human diseases, accounting for one-half or more of all acute illnesses.. Influenza is an acute respiratory illness caused by infection with influenza viruses. . RNA virus. of the family . Orthomyxoviridae. that is responsible for the infectious disease . influenza. (or most commonly referred to as flu) in birds, various mammals (such as pigs) and humans. Typically, influenza is characterized by fever, sore throat, chills and other non-specific symptoms, it is a much more severe disease. It is spread around the world in seasonal epidemics and according to World Health Organization, these annual epidemics result in about three to five million cases of severe illness, and about 250 000 to 500 000 deaths.. Prof & . HoD. Dept Pathology . SKHMC. Influenza virus . General Properties. • Influenza virus is spherical and possesses helical symmetry. • Viral RNA comprises of single stranded RNA. • Site of RNA replication: . Viral infections commonly affect the upper or lower respiratory tract. Although these infections can be classified by the causative virus (. eg. , influenza), they are generally classified clinically according to syndrome (. . Amer. Virus Vaccines. First vaccine developed by Jenner in late 1700's against. smallpox virus. Vaccines. 3. 1796 Jenner: wild type animal-adapted virus. 1800’s Pasteur: Attenuated virus. . College of Medicine & KKUH. Viral Infections of the Respiratory System. Objectives . Introduction to respiratory viral infections. Characteristics of respiratory viruses (. Orthomyxoviridae. , . Paramyxoviridae. Equine influenza. Introduction. Conclusions. References. INTRODUCTION. Equine influenza-epizootic disease of the equine upper . respiratory tract.. To facilitate the understanding of the structure and function, it is convenient to arbitrarily divide the respiratory system into conducting, transitional, and gas exchange systems.. Five Vaccines to Feature for Staff Education. COVID-19, Influenza (Flu), Respiratory Syncytial Virus (RSV), Pneumococcal (Pneumonia) & Shingles . The following information is intended to support your facility’s vaccination education efforts. .