PPT-Chapter 75 Drugs Affecting Calcium Levels and Bone Mineralization

Calcium Physiology Functions and daily requirements Critical to the function of the skeletal nervous muscular and cardiovascular systems Body stores More than 98 stored in the bones Total serum calcium 10 mgdL. DR.RASHMI MINJ. PROF. ./DEAN. GOVT.D.B.GIRLS’P.G.COLLEGE. , RAIPUR. Calcium deficiency is mainly due to inadequate supply of Ca from food or failure of absorption of Ca in the body. .Repeated pregnancy and Lactation with inadequate Calcium supply from food source the Indian women specially who belongs to Low socio income group are the sufferers of Ca deficiency. Bones, . Ligaments,. Cartilage. FUNCTIONS OF skeletal tissues. SUPPORT. : . B. o. nes. form the . FRAMEWORK. of the body and contribute to the shape, alignment, and positioning of body parts;. Larissa Hansen. Definition. Rickets. . is the softening and weakening of bones in children, usually because of an extreme and prolonged vitamin D deficiency.. *. Vitamin . D promotes the absorption of calcium and phosphorus from the gastrointestinal tract. A deficiency of vitamin D makes it difficult to maintain proper calcium and phosphorus levels in bones, which can cause rickets.. Keri Brophy-Martinez. Diseases of Mineral and Bone. Hypercalcemia. Blood calcium levels above expected range. Causes of:. Malignancy. Primary Hyperparathyroidism. Renal Failure. Multiple myeloma. Clinical Symptoms of . Week 9. Chapters 20, 38, & 40. The Skeletal System. Calcium. One of the body’s most important minerals. Responsible for:. Muscle contraction. Nerve conduction. Bone formation. Blood Calcium levels are Controlled by three hormones. Adolescent BoneDevelopment and AlcoholAchieving an optimal peak bone massduring adolescence may reduce a per-s risk for developing osteoporosisie bone loss with fracture later inwithstand a longer dur www.dpcedcenter.org. Next webinar: July 30,2020 .  J.  . Bone Mineral Disorder: Calcium, Vitamin D and Phosphorus. Today’s Presenter. Registered Dietitian for over 6 years. Board Certified Specialist Renal Dietitian . Andrew . Narva. , MD, FASN & . Amy Barton . Pai. , PharmD, MHI, FASN, FCCP, FNKF. Andrew . Narva. , MD, FASN. No financial disclosures/conflicts of interest. Amy Barton . Pai. , PharmD, MHI, FASN, FCCP, FNKF. In general , metabolic bone disease affects the skeleton in one of two ways : there is either too much or too little calcified bone .The latter change , which comprises the majority of metabolic bone disease , is due either to decrease in the amount of bone formed , or to excessive resorption of bone. In turn this may be due to a variety of causes but most commonly to abnormalities of vitamin D and calcium metabolism , which in turn arise from abnormality of diet or renal function , endocrine abnormalities ( particularly of the parathyroid gland) , drug therapy or poisoning .. By Josephine Abraham, Dev Abraham . Calcium Homeostasis. Serum calcium maintained at a constant level. Cellular & tissue effects of calcium depend on blood calcium maintenance within a specific range.. What is osteoporosis?Osteoporosis occurs when the struts that form the mesh-like structure inside bones become thin. This causes the bone to become fragile and break easily, even after a minor bump or Problem . list:. Clinical Q. uestion. What is the causes of . hypocalcemia. . in this patient?. What is the cause of . skeletal deformity . in this patient. ?. What is the . differential diagnosis. of this patient?. PG(Medicine) Dept. of . vcc. , . bvc. Metabolic . bone diseases, . a pathological . conditions affecting multiple . bones and commonly caused by:. Genetic. . N. utritional and/or. Hormonal . abnormalities. The parathyroid glands secrete PTH to help control the levels of calcium and phosphorous in the body. There are usually four parathyroid glands, located on the outside borders of the thyroid gland in the front of the neck..