Ion Channel Dysfunction During
Critical Illness Mark Rich MDPhD Wright State University Case History Weakness and coma in the ICU A 22 year old male developed pneumonia sepsis He was intubated and treated with neuromuscular blocking agents for two weeks He gradually improved and the blocking agents were discontinued but he remained unresponsive with no movement of the limbs for 1 week At this point neurology was consulted to determine why he was paralyzed and unresponsive
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