PPT-New Antiretroviral Drugs in Development and Novel ART Regimens

Constance A Benson MD Professor of Medicine and Global Public Health University of California San Diego La Jolla California Goals for the Workshop To describe the potential benefits of longacting antiretroviral drugs ARVs for treatment and prevention of HIV infection. 500,000 cases annually of MDR TB. Second line treatment toxic and weak. 15% of TB is HIV-related. Drug-drug interactions problematic. 15% of TB is in children. Formulations inadequate, dosages poorly understood. John J. . Faragon. , . PharmD. , BCPS, AAHIV-P. Albany Medical Center Hospital. NY/NJ AIDS Education and Training Center. When to Start. DHHS: Changing Criteria for Initiating ART. CD4+ Count, cells/mm. Brian R. Wood, MD. Assistant Professor of Medicine, University of Washington. Medical Director, NW AETC ECHO. Last Updated. : April 16, 2015. Source: . HHS . Antiretroviral Therapy Guidelines. . AIDS Info (www.aidsinfo.nih.gov). Learning Objectives. Understand when to switch to a second-line regimen. Know preferred second-line regimens for adults (including pregnant and breastfeeding women), adolescents, and children. Describe common drug resistance mutations and how they influence choosing a second-line regimen. Module 10:. Pharmacovigilance. Background – definitions. Timeline of pharmacovigilance for a drug from development (pre-market) to post-marketing use. Burden of adverse drug reactions in children. Number of pharmacoepidemiological safety studies in children (Osokogu et al, 2016). This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the United States and data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.. & HCV . Therapy. Larry Pineda, . PharmD. , . PhC. , BCPS, AAHIVP. Visiting Assistant Professor. UNM College of Pharmacy. Conflicts of Interest Disclosure. No conflicts of interest. 2. Learning Objectives – Pharmacist. implementation of Dolutegravir. Meireles MV. , Pascom ARP, Perini F, Rick F, Benzaken A. . Ministry of Health of Brazil, Department of STI, AIDS and Viral Hepatitis. Acknowledgements. No. . conflicts of interest. G-103 Ckbeceopap (Pubkop( CO>E) (Last updated December 24, 2019, last reviewed December 24, 2019)Carcinogenicity Recommendations for the Use of Antiretroviral Drugs in Pregnant Women with HIV Infectio www.hivguidelines.org. Purpose of . This Guideline. Provide a clear and concise roadmap for clinicians to follow in choosing from among several equally efficacious ART regimens based on individual patient characteristics and preferences.. Haitham. M. Al-. Wali. Ph.D. Pharmacology & Therapeutics. Al-. Nahrain. college of Medicine. 4/3/2016 11:16 AM. 1. The chemotherapy of infections caused by . Mycobacterium tuberculosis. , . M . (Last updated December 30, 2021; last reviewed December 30, 2021) Panel’s Recommendations When acute HIV infection is suspected in pregnancy or during breastfeeding, a plasma HIV RNA test should Transforming the Care of People with HIV . Rajesh T. Gandhi, MD . Massachusetts General Hospital. Harvard Medical School. Boston, Massachusetts. Financial Relationships With Commercial Entities. Dr. Gandhi has served on the scientific . elderly. . individuals. . living. . with. HIV. Catia Marzolini. University Hospital & University of Basel. University of Liverpool. . Disclosures. Research Grant: Gilead. Speaker: . MSD, Gilead.