PPT-New drugs and regimens for TB: 2015 update

Scott K Heysell MD MPH no disclosures Why do we need new drugs regimens Isoniazid and pyrazinamide remain some of the most toxic antibiotics prescribed for infectious disease . Professor Peter Clark. Medical Oncologist. Chair of the NHS England Chemotherapy Reference Group and of the Cancer Drug Fund. Presentation 15 January 2015. 1. Background to English healthcare. The state directs almost all of health service supply (private health insurance held by 9%); total NHS England budget £97bn in 2014/15. KGMU. Top five states in India which have highest number of leprosy cases. State 2009-10 2010-11 2011-12 2012-13. Uttar Pradesh 27,473 25,509 24,627 24,222. 500,000 cases annually of MDR TB. Second line treatment toxic and weak. 15% of TB is HIV-related. Drug-drug interactions problematic. 15% of TB is in children. Formulations inadequate, dosages poorly understood. Scott K. . Heysell. MD, MPH. (no disclosures). Why do we need new drugs/ regimens?. ▪Isoniazid and pyrazinamide remain some of the most . toxic. antibiotics prescribed for infectious disease . -. 2015 Plan Activity Update. Agenda. Gatehouse Update. 2015 . Activity Update. YTD 2015 . Budget. Drainage Update. Insurance . Update. Committee . U. pdates. FAC. Safety & Security. Architectural Review Board . KGMU. Top five states in India which have highest number of leprosy cases. State 2009-10 2010-11 2011-12 2012-13. Uttar Pradesh 27,473 25,509 24,627 24,222. Learning Objectives. Understand when to switch to a second-line regimen. Know preferred second-line regimens for adults (including pregnant and breastfeeding women), adolescents, and children. Describe common drug resistance mutations and how they influence choosing a second-line regimen. U.S. . Public Health Service Guidelines for the Management of Occupational . Exposures . to HIV and Recommendations . for . Postexposure Prophylaxis. . Published August 2013. AETC NRC Slide Set. These slides were developed using the September 2013 updated guidelines on postexposure prophylaxis (PEP) following occupational exposure to HIV. The intended audience is clinicians involved in the care of health care personnel (HCP) with occupational exposure to HIV. . of obstetric anesthesia . Dr SPS. 10/4/2015. 1. Dr. S. Parthasarathy MD., DA., DNB, . MD (. Acu. ), Dip. . Diab. . DCA, . Dip. Software statistics, . PhD (physiology) FICA . Mahatma Gandhi Medical College and Research Institute, . Imperial College London/STFC. Contents. Update. Step IV. Construct/commission/operate/. analyse. Papers. CM43. 2 August 2015. 2. Update. Spokesman’s update. 2 August 2015. 3. Step IV commissioning status. Haitham. M. Al-. Wali. Ph.D. Pharmacology & Therapeutics. Al-. Nahrain. college of Medicine. 4/3/2016 11:16 AM. 1. The chemotherapy of infections caused by . Mycobacterium tuberculosis. , . M . Anastasiya Nestsiarovich, MD, PhD. Postdoctoral Fellow. University of New . Mexico Health Sciences Center. Department of Internal . Medicine. Center . for Global . Health. September 16, 2019. Research team:. R. egimens . m. ay Need . O. ptimization for Youth Failing ART. V Kouamou. , J Manasa, D Katzenstein, A McGregor, CE Ndhlovu, A T Makadzange, PESU Study Team. C. onflict . of . Interest . D. eclaration. Constance A. Benson, MD. Professor of Medicine and Global Public Health. University of California San Diego. La Jolla, California. Goals for the Workshop. To describe the potential benefits of long-acting antiretroviral drugs (ARVs) for treatment and prevention of HIV infection.