PPT-Dopamine pathways & antipsychotics

Pharmacology Instructor Health Sciences Faculty University of Mendoza Argentina Psychiatry Resident Mental Health Teaching Hospital Dr Carlos Pereyra Mendoza Argentina Flavio . Interest in dopamine was intensified by the realisation that dopamine had an important role in the pathogenesis or drug treatment of certain brain History diseases eg Parkinsons disease schizophrenia This lead to much research on the sites of action ANTIPSYCHOTICS ANTIPSYCHOTICS ANTIPSYCHOTICS the facts about the effects C6397 AntiPsychotics Bklt_Version2.indd 1 2/23/10 11:13:03 AM 2 IMPORTANT INFORMATION FOR READERS This report is an overvie Sammy Case & Matt . Vreugde. s.case@warwick.ac.uk. m.vreugde@warwick.ac.uk. . What are the Basal Ganglia. Collection of nuclei in the base of the forebrain. Predominantly modulate descending motor signals from cortex to cerebellum. A command and control center for our simultaneous multiple constraint satisfying machine. . Outline. Staying alive and maintaining Homeostasis. P. erception. Motivation and Effort. Emotions & Habits. Psychosis. a state in which a person’s mental capacity to recognize reality, communicate, and relate to others is impaired. delusions, hallucinations (auditory, visual, tactile, olfactory), grossly disorganized thinking in a sensible manner . Emotion. Emotion will be a central element in our . account of the neuroscience of consciousness.. The systems that underlie what we think of as emotion provide a way to account for saliency, what grabs our attention.. Philip . Cofoid. Prevalence of 0.3% to 0.5% worldwide. Before antipsychotic drugs, the outcome of schizophrenia usually resulted in:. Catatonic states. Institutionalization. Complete debilitation. Antipsychotics have not only made schizophrenia manageable, they immensely improve the quality of life of the patients. “The Scream” 1893 . Objectives. Understand the impact of psychotic disorders on individuals, families, and society. Describe the sources of dysfunction in major life areas in individuals with schizophrenia. Pharmacology Instructor. Health Sciences Faculty. University of Mendoza. Argentina. Psychiatry Resident. Mental Health Teaching Hospital “Dr. Carlos . Pereyra. “ . Mendoza. Argentina. Flavio. . aherman@buffalo.edu. Goals. Brief . o. verview of material covered thus far. Highlight important, exam-relevant material. Provide a space for questions and discussion. These reviews should help guide your studying!. Department of Pharmacology and Neuroscience. Texas Tech University Health Sciences Center. Lubbock, TX.. 1. 0. Antipsychotic Drugs ; Learning Objectives:. 2. 0. 1. Discuss . role of dopamine and serotonin in the . Other sources of information Databases In the third quarter of 2005 the database of the WHO contained 3317 ADRs associated with the use of quetiapine. A total of 396 ADRs concern an extrapyramidal dis Antipsychotic drugs. 1. Dopamine- serotonin hypothesis of schizophrenia. 2. Classification of antipsychotic drugs. 3. Basic concepts about their receptors action. 4. Basic concepts about their related effects/ side effects and how to manage them. Greg Raczkowski, MS-IV. John DiMeglio, MS-IV. Jacobs School of Medicine & Biomedical Sciences. 1/31/2020. Our Goals. Brief overview of material from this week. Highlight relevant exam/board material.