PDF-MOLECULAR STRUCTURE OF NUCLEIC ACIDS A Structure for D

NA ThiR structure has novel f8tUIW which 8IX3 of considereblc biological intewst A structure for nucleic acid has already been proposed by p8uling and Corey They kindly m8de their manuscript 8vailablo to us in 8dvence of publication Their model conht. 2. Proteins. Proteins are polymers made of monomers called amino acids. All proteins are made of 20 different amino acids linked in different orders. Proteins are used to build cells, act as hormones & enzymes, and do much of the work in a cell. The Protein Data Bank. Swanand. Gore & Gerard . Kleywegt. PDBe. – EBI. May 7. th. 2010, 9-10 am. Macromolecular Crystallography Course. Outline. Structural Biology and Bioinformatics. Databases in Structural Bioinformatics. Nucleic Acids. What do we know already?. i. . The nucleic acids DNA and RNA are polymers of nucleotides. Nucleotides consist of 3 parts. A 5-carbon sugar – ribose or deoxyribose. A phosphate group (acidic & negatively-charged). polymers. four major classes of biologically important organic molecules: . carbohydrates. lipids. proteins . (and related compounds). nucleic acids . (and related compounds). Discuss hydrolysis and condensation, and the connection between them.. Essential idea: The structure of DNA allows efficient storage of genetic information.. There is 2m of DNA in each human cell, however the most cells in the human body have a diameter of 10 . μm. . This DNA is divided in chromosomes and coiled around proteins called histones so that it can be efficiently stored in each cell's nucleus. The human genome project which has decoded the case sequence for the whole 2m of the human genome requires a data warehouse (pictured) to store the information electronically. This should give a good idea of just how efficient DNA is at storing information and why it needs to be so.. Attractive force between particles of the same kind. ____________________. Attractive force between unlike substances. _______________________. In a mixture of water and cool-aid which would be the solute and which would be the solvent?. Biochemistry-Macromolecules 4 types Carbohydrates Lipids Proteins Nucleic Acids Carbohydrates Function of Carbohydrates Energy source!!! Energy is stored in the C-H bonds Plant Structure Cellulose is a carbohydrate found in the cell wall of plants 1. Heredidity. Heredity. is the transfer of characteristics anatomical as well as biochemical, from generation to generation. . The transmission of hereditary information from one generation to another takes place in the nucleus of the cell, . Dr. Mohammed Hussein. M.B.Ch.B, MSC, DCH (UK), MRCPCH. Molecular Biology. Main Topics . Nucleic acid structure . and . organization. DNA replication and repair. Transcription . and RNA . processing. The genetic code, mutation, and translation. The Double Helix (DNA). Structural model:. Model proposed by Watson & Crick, 1953. Two sugar-phosphate strands, next to each other, but running in opposite directions.. Specific Hydrogen bonds. occur among bases from one chain to the other:. Each nucleic acid has its own unique sequence of bases that carries the genetic information from one cell to the next.. Learning . Goal . Describe the primary structures of DNA . and RNA. .. Nucleic Acid Structure. 16 Atomic structure of DNA,by Madeleine Price Ball (Wikimedia Commons) Topic Objectives TaskBloom’sBIOL 102 CoreCoreto explain DNA polarity notationtemperature on DNA structure MOLECULAR GENETICS , Function & Repair . Lecturer 7 . Dr. . . Shaimaa. . Munther. . Organelles of the cell. . . Living organisms are made up of cells Each of these cells have a viscous substance called . cytoplasm. Lecturer 7 . Dr. . Shaimaa. . Munther. . General. . Introduction. . Nucleic acids are required for the storage and expression of genetic information. . There are two chemically distinct types of nucleic acids: (.