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Human Genetics Human Genetics

Human Genetics - PDF document

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Human Genetics - PPT Presentation

Sexlinked DisordersBiologySexLinked TraitsSexlinked traits are produced by genes only on the X chromosome They can be Dominant or RecessiveA dominant a recessiveWhat would be the genotypes of ID: 859115

linked sex recessive trait sex linked trait recessive female male traits affected disorders blindness dominant lead normal absence red

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1 Human Genetics Sex - linked Disorders
Human Genetics Sex - linked Disorders Biology Sex - Linked Traits  Sex - linked traits are produced by genes only on the X chromosome.  They can be Dominant or Recessive.  A = dominant a = recessive  What would be the genotypes of a male and female that have a Sex - linked Dominant trait and do not express the trait?  Expresses Trait: Male - X

2 A Y Female - X A X A or
A Y Female - X A X A or X A X a  No Expression: Male - X a Y Female - X a X a  What would be the genotypes of a male and female that have a Sex - linked Recessive trait and do not express the trait?  Expresses Trait: Male - X a Y Female - X a X a  No Expression: Male - X A Y Fe

3 male - X A X A
male - X A X A or X A X a (Carrier)  Most Sex - linked traits are Recessive ! Sex - Linked Recessive Traits  More males than females are affected.  An affected son can have parents who have the normal phenotype. (X A Y x X A X a )

4  For a daughter to have the trait, he
 For a daughter to have the trait, her father must also have it. Her mother must have it or be a carrier. ( X a Y , X a X a , X A X a )  The trait often skips a generation from the grandfather to the grandson.  If a woman has the trait ( X a X a ), all of her sons will be affected. Examples of Sex - Linked Recessive Disorders  Red/Green Colorblindness – Diff

5 iculty perceiving differences between c
iculty perceiving differences between colors (red or green, blue or yellow).  Hemophilia – Absence of one or more proteins necessary for normal blood clotting.  Deafness  Cataracts – opacity in the lens that can lead to blindness Examples of Sex - Linked Recessive Disorders, continued…  Night blindness – ( Nyctalopia ) rods do not work so that can n

6 ot see in the dark  Glaucoma â€
ot see in the dark  Glaucoma – pressure in the eye that can lead to optic nerve damage and blindness  Duchenne Muscular Dystrophy – progressive weakness and degeneration of skeletal muscles that control movement due to absence of dystrophin (protein that maintains muscle integrity). Mainly in boys, onset 3 - 5 yrs, by 12 years can’t walk, and later needs respira