β deposits from brain biopsy tissue Color image before analysis A β deposits are shown in brown colored immunostain This image has been flat field corrected for uneven illumination ID: 913055
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Figure e-2. Semi
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quantification of Aβ deposits from brain biopsy tissue. Color image before analysis. Aβ deposits are shown in brown colored immunostain. This image has been flat field corrected for uneven illumination. Threshold image showing Aβ deposits (black), that were selected by software for quantification. A single optimal threshold value irrespective of size, shape and intensity of Aβ deposits was used. Vascular Aβ was excluded from the analysis.
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