PPT-Prudence in Germline Gene Editing

The Urgent Need for Collaborative Partnerships in Africa Dr Gerald Michael Ssebunnya AFRICA INSTITUTE FOR HUMAN DIGNITY gmshumandignityafricacom GFBR Meeting 2019 Singapore 12 th 13. Societal Implications of Emerging Technologies . . Continue . research on . somatic. . gene editing . with due oversight and ethical, social, and legal studies . Set . Moratorium. . on . basic research . Of Which People, By Which People, For Which People?. Charis Thompson. Chancellor’s Professor . UC Berkeley / London School . of Economics. Washington, DC, December 2015. Consensus on Human . Germline. Fyodor D. Urnov, PhD. Project Leader and Senior Scientist, Sangamo BioSciences, Inc.. NAS International . Summit on Human Gene . Editing. December 3, 2015. Genome Editing . Is. In the Clinic. Fyodor D. Urnov, PhD. Fyodor D. Urnov, PhD. Project Leader and Senior Scientist, Sangamo BioSciences, Inc.. NAS International . Summit on Human Gene . Editing. December 3, 2015. Genome Editing . Is. In the Clinic. Fyodor D. Urnov, PhD. law. 1994. Civil code: . Art. 16-4. . <<. . No one may infringe upon the integrity of mankind. . << . Any eugenic practice which aims at organizing the selection of persons is forbidden. Kyle Orwig. Magee-. Womens. Research Institute. University of Pittsburgh School of Medicine. International Summit on Human Gene Editing:. A Global Discussion. December 1-3, 2015. Stem Cell. Renewal. Andrew May DPhil Chief Scientific Officer Caribou Biosciences, Inc. 2/11/2016 1 Gene Editing Tools and Methods Caribou background Founded by Jennifer Doudna , Rachel Haurwitz , Martin Jinek and James Berger (UC Berkeley) to develop commercial applications 12 – 13 November 2019, Singapore. www.gfbr.global.  .  .  .  . The GFBR. Funded by Bill & Melinda Gates Foundation, UK Medical Research Council, US National Institutes of Health, and . Wellcome. How can we advance CRISPR from a revolutionary research tool to a level of precision and efficiency that will enable us to target ANY genetic disease?. DUAL OMNI™ . TECHNOLOGY PLATFORMS. Novel CRISPR Nuclease Discovery Platform. We performed a genome-wide analysis of gene expressionto identify germline- and sex-regulated genes.Using mutants that cause defects in germ cell proliferationor gametogenesis, we identiÞed sets of g Propelled by the promise of faster, cheaper, and more accurate by CRISPR-Cas gene editing. For all of their ease and rapidity, cell or gene therapy. The generation of unintended DNA strand its niche w ICH Considerations General Principles to Address the Risk of Inadvertent Germline Integration of Gene Therapy Vectors TRANSMISSION TO CHMP November 2006 RELEASED FOR INFORMATION November 2006 Ethics, governance and policy aspects of human genome editing research . . Maneesha S Inamdar. JNCASR, Bangalore. GFBR. 12-13 Nov 2019. Singapore. Maneesha S Inamdar. Professor and Chair. Molecular Biology and Genetic Unit. the. . Brazilian. . regulatory. framework: . can. . we. face . genome. . editing. ?. José Ricardo Jensen, DVM, Former Head, CEUAIB (IACUC - Instituto Butantan). Ricardo Palacios, Clinical R&D Manager - Division of Clinical Trials and Pharmacovigilance .