PPT-The Immunopathogenesis of Rheumatoid Arthritis and Immunologically Targeted Therapy

Alan L Epstein MD Clinical Professor of Medicine University of Pennsylvania School of Medicine Disclosures Speakers Bureau and Consultant Abbvie Amgen AstraZeneca BMS Chemocentryx Fresenius . The good news is that the outlook has greatly improved for many people with newly diagnosed detected RA Of course RA remains a serious disease and one that can vary widely in symptoms what you feel and outcomes Even so treatment advances have made By, Marissa Miuccio. Definition. What is it. Rheumatoid arthritis is a chronic inflammatory disorder that typically affects the small joints in your hands and feet. Rheumatoid arthritis affects the lining of your joints causing a painful swelling that can eventually result in bone erosion and bone deformity. . PHM 142. Yunfan Zhang, Jingyi Qiu, Jeffrey Lai, Yifan Zhou. PHM142 Fall . 2016. Coordinator. : Dr. Jeffrey Henderson. Instructor: Dr. David Hampson. Clinical representation of rheumatoid arthritis .  . Arthritis, Dermatitis, Migraine. Osteoarthritis (OA).  . -involves swelling of the joints.  . -overweight – causes wear of cartilaginous surfaces.  . -such wear results in loss of chondroitin sulphate and glucosamine which are carbohydrate polymers. Dr R B Kalia,. Additional Professor ,. Department of Orthopaedics. Leaning Objective. Clinical Features of RA. Investigations . Diagnosis. Indications for Surgery in Arthritis. Various procedures possible. Rheumatoid Arthritis . Inflammatory vs Noninflammatory Arthritis. ACR/EULAR Criteria for Diagnosing RA Before Joint Damage. Limitations to Classification of RA. Biomarkers in RA. Differential Diagnosis. FRCPEdin. ; . FRCSEdin. “A . chronic progressive disease causing inflammation in the joints and resulting in painful deformity and immobility, especially in the fingers, wrists, feet, and . ankles”.. FRCPEdin. ; . FRCSEdin. “A . chronic progressive disease causing inflammation in the joints and resulting in painful deformity and immobility, especially in the fingers, wrists, feet, and . ankles”.. FRCPEdin. ; . FRCSEdin. “A . chronic progressive disease causing inflammation in the joints and resulting in painful deformity and immobility, especially in the fingers, wrists, feet, and . ankles”.. : Autoimmune disease that causes chronic inflammation of connective tissue. Joint tissue is permanently affected, but any connective tissue of the body might be involved.. Etiology. : Associated with the production of abnormal antibodies that attacks or attaches to the bodies own cells and tissues. Presence of the antibody called Rheumatoid factor (RF) in the affected individuals blood is indicative of the disease.. Gregory Gardner, M.D.. Gilliland-Henderson. Professor of Medicine. Division of Rheumatology. University of Washington. Outline of Discussion. Pathophysiology. Clinical Features. Treatment Update. Perioperative Management. Abstract Objective: Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA Address for Correspondence: Rajaie Namas, Division of Rheumatology, Department Sonya Abraham. Senior Lecturer/Honorary . Consultant. Imperial College Healthcare NHS Trust. Medical . Student Lecture (Yr 5). May 2012. Rheumatoid Arthritis. Historical. Epidemiology. Disease Pathogenesis. . therapy. Systemic. . autoimmune. . diseases. Rheumatoid. arthritis. Juvenile. arthritis. Systemic. lupus . erythematodes. Sclerodermia. Sjogren. syndrom. - . Polymyalgia. . rheumatica. Spondylartritis.