PPT-Tuberculosis INTRODUCTION

TB has existed since antiquity T he oldest unambiguously detected mycobacterium tuberculosis give evidence of the disease in the remains of bison in Wyoming dated around 17000 years ago TB in human can be traced back ti 9000 years ago in Haifa archeologists found TB in remains of mother and child buried together. When someone who is sick with TB coughs speaks laughs sings or sneezes people nearby may breathe TB bacteria into their lungs TB usually attacks the lungs but can also attack other parts of the body such as the brain spine or kidneys There are two t Government stewardship and accountability with monitoring and evaluation 2 Strong coalition with civil society organizations and communities 3 Protection and promotion of human rights ethics and equity 4 Adaptation of the strategy and targets at cou . . VDH TB Control and Prevention Program. Tuberculosis (TB) adalah penyakit granulamatosa menular, disebabkan oleh kuman genus . Mycobacterium. , berbentuk batang, Gram-positif, dan bersifat tahan asam. Penyakit umumnya berlangsung secara kronis, dan sangat melemahkan (debilitating). *. Morlan. Serrano Diana . Guadalupe Grupo: 1301. *. Santiago . Díaz . Ana . María. *Sánchez González . Sarai. ¿. Qué es?. Enfermedad infecciosa crónica, que llega a provocar zoonosis, causada por bacterias del genero . ries 14 61 contributed data on 17690 isolates whichThese drugs are more costly toxic and less effective thanfirst-line drugs used for routine treatment of TB with other diseases resistance to TB drugs Dr.. . Mohed. Shaker. A Brief History of Tuberculosis (TB). Tuberculosis (phthisis) described since the time of . Hippocrates (460 BC - 370 BC). . 1689: Doctor Richard Morton . used the term . “consumption”. Dr.. . Mohit. Bhatia. Assistant Professor. Department of Microbiology. AIIMS, . Rishikesh. LAYOUT. Introduction to Mycobacteria. Laboratory Diagnosis. General Features of Mycobacteria. Acid fastness . Case Presentation. . Imaging. Bibliography. Discussion. Gastrointestinal tuberculosis accounts for 1% to 3 % of all TB cases worldwide. . Common manifestations are Esophageal TB, Gastric and Gastroduodenal TB, TB of small and large intestine, Rectal and anal TB, and peritoneal TB [1] [2]. . Cosivi O, Grange J, Daborn C, Raviglione M, Fujikura T, Cousins D, et al. Zoonotic Tuberculosis due to Mycobacterium bovis in Developing Countries. Emerg Infect Dis. 1998;4(1):59-70. https://doi.org/10.3201/eid0401.980108. Mycobacteria are . aerobic, acid-fast bacilli (rods. ). They are neither gram-positive nor gram-negative (i.e., they are stained poorly by the dyes used in Gram stain).. The term . acid-fast . refers to an organism’s ability to retain the carbolfuchsin stain despite subsequent treatment with an ethanol–hydrochloric acid mixture.. Sola C, Devallois A, Horgen L, Maïsetti J, Filliol I, Legrand E, et al. Tuberculosis in the Caribbean: Using Spacer Oligonucleotide Typing to Understand Strain Origin and Transmission. Emerg Infect Dis. 1999;5(3):404-411. https://doi.org/10.3201/eid0503.990311. . The most common manifestation of CNS tuberculosis is leptomeningitis with enhancing basal exudates. Ventricular involvement is uncommon and occurs in late stages of disseminated. . TB. . meningitis.. General Features of Mycobacteria. Acid fastness . due to . Mycolic acids in the cell wall & Integrity of the cell wall. ™. Guanine plus cytosine (G+C) content of DNA of . Mycobacterium is 61–71 mol % (exception .